ICC (Immunocytochemistry)
(Immunocytochemistry of CARD10 in EL4 cells with CARD10 antibody at 10 ug/mL.)
Rabbit anti-Human, Mouse CARD10 Polyclonal Antibody | anti-CARD10 antibody
CARD10 Antibody
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
immunoaffinity purified
Synonyms
CARD10, Antibody; CARD10 Antibody; Caspase recuitment domain family 10, CARMA3, Bimp1; anti-CARD10 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
immunoaffinity purified
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1032
Applicable Applications for anti-CARD10 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10.
Target Name
CARD10
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of CARD10 in EL4 cells with CARD10 antibody at 10 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of CARD10 in EL4 cells with CARD10 antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of CARD10 expression in EL4 cell lysate with CARD10 antibody at (A) 5 and (B) 10 ug /ml.)
WB (Western Blot)
(Western blot analysis of CARD10 expression in EL4 cell lysate with CARD10 antibody at (A) 5 and (B) 10 ug /ml.)
Related Product Information for anti-CARD10 antibody
Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10. This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-kB. CARD 10 and the related protein CARMA1 also associate with NEMO, the regulatory subunit of the IkK complex, demonstrating its importance in the regulation of NF-kB transcription factor activation.
Product Categories/Family for anti-CARD10 antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
82,541 Da
NCBI Official Full Name
caspase recruitment domain protein 10
UniProt Protein Name
Caspase recruitment domain-containing protein 10
UniProt Gene Name
CARD10
UniProt Synonym Gene Names
CARMA3; Carma 3
UniProt Entry Name
CAR10_HUMAN
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Product Notes
The CARD10 card10 (Catalog #AAA304849) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CARD10 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CARD10 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the CARD10 card10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CARD10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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