Rabbit anti-Human, Mouse CARD10 Polyclonal Antibody | anti-CARD10 antibody

CARD10 Antibody

Cat. Num. AAA40413

• Gene Names: CARD10; BIMP1; CARMA3
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: CARD10 Antibody is immunoaffinity purified.
• Synonyms: CARD10, Antibody; CARD10 Antibody; CARD10; BIMP1; CARMA3; Caspase recruitment domain-containing protein 10; CARD-containing MAGUK protein 3; Carma 3; caspase recruitment domain family, member 10; anti-CARD10 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: CARD10 Antibody is immunoaffinity purified.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1032

• Applicable Applications for anti-CARD10 antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: CARD10 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10.
• Buffer: CARD10 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: CARD10 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of CARD10 in EL4 cells with CARD10 antibody at 20 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of CARD10 in EL4 cells with CARD10 antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of CARD10 in A-20 cell lysate with CARD10 antibody at 5 μg/mL.)

Related Product Information for anti-CARD10 antibody

CARD10 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10. This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-κB. CARD 10 and the related protein CARMA1 also associate with NEMO, the regulatory subunit of the IκK complex, demonstrating its importance in the regulation of NF-κB transcription factor activation.

NCBI and Uniprot Product Information

• NCBI GI #: 13488607
• NCBI GeneID: 29775
• UniProt Accession #: Q9BWT7; Q14CQ8; Q5TFG6; Q8NC81; Q9UGR5; Q9UGR6; Q9Y3H0
• Molecular Weight: 82,541 Da
• NCBI Official Full Name: caspase recruitment domain protein 10
• NCBI Official Synonym Full Names: caspase recruitment domain family, member 10
• NCBI Official Symbol: CARD10
• NCBI Official Synonym Symbols: BIMP1; CARMA3
• NCBI Protein Information: caspase recruitment domain-containing protein 10; carma 3; CARD-containing MAGUK 3 protein; CARD-containing MAGUK protein 3; Bcl10 binding protein and activator of NFKB
• UniProt Protein Name: Caspase recruitment domain-containing protein 10
• UniProt Gene Name: CARD10
• UniProt Synonym Gene Names: CARMA3; Carma 3
• UniProt Entry Name: CAR10_HUMAN