FCM/FACS (Flow Cytometry)
(CASC4 Antibody (C-term) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit anti-Human, Mouse CASC4 Polyclonal Antibody | anti-CASC4 antibody
CASC4 Antibody (C-term)
Gene Names
CASC4; H63
Reactivity
Human, Mouse
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Synonyms
CASC4, Antibody; CASC4 Antibody (C-term); Protein CASC4; Cancer susceptibility candidate gene 4 protein; CASC4; anti-CASC4 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.
Purity/Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Length
415
Applicable Applications for anti-CASC4 antibody
FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
Antigen Region
336-365
Cellular Location
Membrane; Single-pass type II membrane protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(CASC4 Antibody (C-term) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(CASC4 Antibody (C-term) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
WB (Western Blot)
(CASC4 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CASC4 antibody detected the CASC4 protein (arrow).)
WB (Western Blot)
(CASC4 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CASC4 antibody detected the CASC4 protein (arrow).)
Related Product Information for anti-CASC4 antibody
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.
Product Categories/Family for anti-CASC4 antibody
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Sato, T., et al. Onkologie 26(3):268-271(2003)
Scheer, M., et al. Mund Kiefer Gesichtschir 7(3):138-145(2003)
Oh, J.J., et al. Nucleic Acids Res. 27(20):4008-4017(1999)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Sato, T., et al. Onkologie 26(3):268-271(2003)
Scheer, M., et al. Mund Kiefer Gesichtschir 7(3):138-145(2003)
Oh, J.J., et al. Nucleic Acids Res. 27(20):4008-4017(1999)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49498
NCBI Official Full Name
protein CASC4 isoform a
NCBI Official Synonym Full Names
cancer susceptibility candidate 4
NCBI Official Symbol
CASC4
NCBI Official Synonym Symbols
H63
NCBI Protein Information
protein CASC4
UniProt Protein Name
Protein CASC4
UniProt Gene Name
CASC4
UniProt Entry Name
CASC4_HUMAN
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Product Notes
The CASC4 casc4 (Catalog #AAA289126) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CASC4 Antibody (C-term) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CASC4 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CASC4 casc4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASC4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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