WB (Western Blot)
(Anti-Caspase-1(P20) antibody, AAA11584, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Spleen Tissue LysateLane 3: Mouse Brain Tissue LysateLane 4: Mouse Spleen Tissue LysateLane 5: Mouse Testis Tissue Lysate)
Rabbit anti-Mouse, Rat Caspase-1(P20) Polyclonal Antibody | anti-CASP1 antibody
Polyclonal Anti-CASP1 (p20) Antibody
Gene Names
Casp1; ICE; Il1bc
Reactivity
Mouse, Rat
Applications
Western Blot
Purity
Immunogen affinity purified.
Synonyms
Caspase-1(P20), Antibody; Polyclonal Anti-CASP1 (p20) Antibody; anti-CASP1 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized; Contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
Sequence Length
402
Applicable Applications for anti-CASP1 antibody
Western Blot (WB)
Application Notes
Western Blot:
Concentration: 0.1-0.5ug/ml
Tested Species: Ms, Rat
Predicted Species: -
Antigen Retrieval: -
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Concentration: 0.1-0.5ug/ml
Tested Species: Ms, Rat
Predicted Species: -
Antigen Retrieval: -
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of mouse CASP1 (137-157aa LEKAQKLWKENPSEIYPIMNT), different from the related rat sequence by three amino acids.
Reconstitution
0.2ml of distilled water will yield a concentration of 500ug/ml.
Recommended Detection Systems
We provide a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit in WB.
Preparation and Storage
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time.
Avoid repeated freezing and thawing.
It can also be aliquotted and stored frozen at -20°C for a longer time.
Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti-Caspase-1(P20) antibody, AAA11584, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Spleen Tissue LysateLane 3: Mouse Brain Tissue LysateLane 4: Mouse Spleen Tissue LysateLane 5: Mouse Testis Tissue Lysate)
WB (Western Blot)
(Anti-Caspase-1(P20) antibody, AAA11584, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Spleen Tissue LysateLane 3: Mouse Brain Tissue LysateLane 4: Mouse Spleen Tissue LysateLane 5: Mouse Testis Tissue Lysate)
Related Product Information for anti-CASP1 antibody
Caspase 1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, IL18, and IL33 precursor proteins. It belongs to a family of cysteine proteases known as caspases that always cleave proteins following an aspartic acid residue. The Caspase1 gene consists of 10 exons spanning at least 10.6 kb. The Caspase 1 gene is mapped to 11q23, a site frequently involved in rearrangement in human cancers, including a number of leukemias and lymphomas, by Southern DNA blot analysis of rodent-human hybrids and by in situ hybridization to normal human metaphase chromosomes. Caspase 1 has been shown to induce cell necrosis or pyroptosis and may function in various developmental stages.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Caspase-1
NCBI Official Synonym Full Names
caspase 1
NCBI Official Symbol
Casp1
NCBI Official Synonym Symbols
ICE; Il1bc
NCBI Protein Information
caspase-1; p45; CASP-1; IL-1BC; IL-1B converting enzyme; IL-1 beta-converting enzyme; interleukin-1 beta convertase; interleukin 1 beta-converting enzyme; interleukin-1 beta-converting enzyme
UniProt Protein Name
Caspase-1
UniProt Gene Name
Casp1
UniProt Synonym Gene Names
Il1bc; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme
UniProt Entry Name
CASP1_MOUSE
Similar Products
Product Notes
The CASP1 casp1 (Catalog #AAA11584) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Anti-CASP1 (p20) Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Caspase-1(P20) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: Concentration: 0.1-0.5ug/ml Tested Species: Ms, Rat Predicted Species: - Antigen Retrieval: - Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. Researchers should empirically determine the suitability of the CASP1 casp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caspase-1(P20), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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