IHC (Immunohiostchemistry)
(Anti-Caspase 4 antibody, AAA45079, IHC(P)IHC(P): Human Mammary Cancer Tissue)
Rabbit anti-Human Caspase 4 Polyclonal Antibody | anti-CASP4 antibody
Anti-Caspase 4 antibody
Gene Names
CASP4; TX; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Caspase 4, Antibody; Anti-Caspase 4 antibody; Caspase-4; caspase 4, apoptosis-related cysteine peptidase; Apoptosis related cysteine peptidase antibody; Apoptotic cysteine protease Mih1/TX antibody; CASP 4 antibody; CASP-4 antibody; CASP4 antibody; CASP4_HUMAN antibody; Caspase 4 apoptosis related cysteine peptidase antibody; Caspase-4 subunit 2 antibody; Caspase4 antibody; ICE(rel) II antibody; ICE(rel)-II antibody; ICE(rel)II antibody; ICEREL II antibody; ICERELII antibody; ICH 2 antibody; ICH 2 protease antibody; ICH2 antibody; Mih1/TX antibody; Protease ICH-2 antibody; Protease TX antibody; TX antibody; TX protease antibody; anti-CASP4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
377
Applicable Applications for anti-CASP4 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase 4 (104-124aa DALKLCPHEEFLRLCKERAEE).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-Caspase 4 antibody, AAA45079, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Caspase 4 antibody, AAA45079, IHC(P)IHC(P): Human Mammary Cancer Tissue)
WB (Western Blot)
(Anti-Caspase 4 antibody, AAA45079, Western blottingAll lanes: Anti Caspase 4 (AAA45079) at 0.5ug/mlLane 1: MCF-7 Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: JURKAT Whole Cell Lysate at 40ugLane 4: CEM Whole Cell Lysate at 40ugLane 5: SW620 Whole Cell Lysate at 40ugPredicted bind size: 43KDObserved bind size: 20KD)
WB (Western Blot)
(Anti-Caspase 4 antibody, AAA45079, Western blottingAll lanes: Anti Caspase 4 (AAA45079) at 0.5ug/mlLane 1: MCF-7 Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: JURKAT Whole Cell Lysate at 40ugLane 4: CEM Whole Cell Lysate at 40ugLane 5: SW620 Whole Cell Lysate at 40ugPredicted bind size: 43KDObserved bind size: 20KD)
Related Product Information for anti-CASP4 antibody
Description: Rabbit IgG polyclonal antibody for Caspase-4(CASP4) detection. Tested with WB, IHC-P in Human.
Background: Caspase 4 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. The Caspase 4 gene is mapped to a P1 clone containing the ICE gene, which is located at chromosome 11q22.2-q22.3. It contains 8 coding exons.The function of caspase 4 is not fully known, but it is believed to be an inflammatory caspase, along with caspase 1, caspase 5(and the murine homolog caspase 11), with a role in the immune system.
Background: Caspase 4 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. The Caspase 4 gene is mapped to a P1 clone containing the ICE gene, which is located at chromosome 11q22.2-q22.3. It contains 8 coding exons.The function of caspase 4 is not fully known, but it is believed to be an inflammatory caspase, along with caspase 1, caspase 5(and the murine homolog caspase 11), with a role in the immune system.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
36,705 Da
NCBI Official Full Name
Caspase-4
NCBI Official Synonym Full Names
caspase 4, apoptosis-related cysteine peptidase
NCBI Official Symbol
CASP4
NCBI Official Synonym Symbols
TX; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
NCBI Protein Information
caspase-4; CASP-4; ICE(rel)-II; protease TX; protease ICH-2; apoptotic cysteine protease Mih1/TX; caspase 4, apoptosis-related cysteine protease
UniProt Protein Name
Caspase-4
UniProt Gene Name
CASP4
UniProt Synonym Gene Names
ICH2; CASP-4
UniProt Entry Name
CASP4_HUMAN
Similar Products
Product Notes
The CASP4 casp4 (Catalog #AAA45079) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Caspase 4 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Caspase 4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CASP4 casp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caspase 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.