IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Rat brain tissue with CASR Polyclonal Antibody.)
Rabbit anti-Mouse, Rat CASR Polyclonal Antibody | anti-CASR antibody
CASR Polyclonal Antibody
Gene Names
CASR; CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; hCasR; GPRC2A; HYPOC1
Reactivity
Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Purification
Synonyms
CASR, Antibody; CASR Polyclonal Antibody; anti-CASR antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
1078
Applicable Applications for anti-CASR antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Synthetic Peptide
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Rat brain tissue with CASR Polyclonal Antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Rat brain tissue with CASR Polyclonal Antibody.)
WB (Western Blot)
(Western Blot analysis of 1) Mouse brain, 2) Rat brain using CASR Polyclonal Antibody at dilution of 1:20000.)
WB (Western Blot)
(Western Blot analysis of 1) Mouse brain, 2) Rat brain using CASR Polyclonal Antibody at dilution of 1:20000.)
Related Product Information for anti-CASR antibody
CASR (Calcium Sensing Receptor) is a Protein Coding gene. Diseases associated with CASR include Hypocalcemia, Autosomal Dominant and Hyperparathyroidism, Neonatal. Among its related pathways are Proton Pump Inhibitor Pathway, Pharmacodynamics and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and protein kinase binding. An important paralog of this gene is GPRC6A.The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
130kDa
NCBI Official Full Name
extracellular calcium-sensing receptor isoform 2
NCBI Official Synonym Full Names
calcium sensing receptor
NCBI Official Symbol
CASR
NCBI Official Synonym Symbols
CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; hCasR; GPRC2A; HYPOC1
NCBI Protein Information
extracellular calcium-sensing receptor
UniProt Protein Name
Extracellular calcium-sensing receptor
UniProt Gene Name
CASR
UniProt Synonym Gene Names
PCaR1
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Product Notes
The CASR casr (Catalog #AAA173743) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CASR Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CASR can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CASR casr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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