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product-image-AAA13859_IF6.jpg IF (Immunofluorescence) (Immunofluorescence - anti-CTSD Ab at 1/100 dilution in RAW264.7 cells; cells were fixed with PFA and permeabilized with 0.05% saponin)

Goat Cathepsin D Polyclonal Antibody | anti-CTSD antibody

Cathepsin D Polyclonal Antibody

Gene Names
CTSD; CPSD; CLN10; HEL-S-130P
Reactivity
Reacts against human, rat, mouse, canine and monkey proteins.
Applications
Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry
Synonyms
Cathepsin D, Antibody; Cathepsin D Polyclonal Antibody; Anti-Cathepsin D; ceroid-lipofuscinosis,; CLN10; CPSD; CTSD; lysosomal aspartyl protease; lysosomal aspartyl peptidase; neuronal 10 antibody; anti-CTSD antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Reacts against human, rat, mouse, canine and monkey proteins.
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody gives a positive signal in the following human (Jurkat, HT1080, HUH, MDA-MB-231, ARPE19, SH-SY5Y), canine (MDCK) and monkey (COS-7) whole cell lysates.
Form/Format
Polyclonal antibody supplied as 200 uL (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Sequence Length
412
Applicable Applications for anti-CTSD antibody
Western Blot, Immunofluorescence, Immunohistochemistry (paraffin), Immunohistochemistry (frozen), IEM
Application Notes
Western Blot: 1:250-1:1,000
Immunofluorescence 1:50-1:200
Immunohistochemistry (paraffin) 1:50-200
Immunohistochemistry (frozen) 1:50-1:200
IEM 1:50-1:200
Immunogen
Purified recombinant peptide derived from within residues 275 aa to the C-terminus of human Cathepsin D produced in E. coli.
Preparation and Storage
Store at -20°C for long term storage.
Store at 2-8°C for up to one month.

Avoid freeze/thaw cycles.

IF (Immunofluorescence)

(Immunofluorescence - anti-CTSD Ab at 1/100 dilution in RAW264.7 cells; cells were fixed with PFA and permeabilized with 0.05% saponin)

product-image-AAA13859_IF6.jpg IF (Immunofluorescence) (Immunofluorescence - anti-CTSD Ab at 1/100 dilution in RAW264.7 cells; cells were fixed with PFA and permeabilized with 0.05% saponin)

IF (Immunofluorescence)

(Immunofluorescence- anti CTSD at 1/100 dilution in NHI/3T3; cells were fixed with methanol and permeabilized with 0.1% saponin)

product-image-AAA13859_IF5.jpg IF (Immunofluorescence) (Immunofluorescence- anti CTSD at 1/100 dilution in NHI/3T3; cells were fixed with methanol and permeabilized with 0.1% saponin)

Application Data

(Immunogold lableing using melanocytes and anti-CTSDS Ab)

product-image-AAA13859_APP4.jpg Application Data (Immunogold lableing using melanocytes and anti-CTSDS Ab)

Application Data

(Immunoperoxidase of polyclonal antibody to CTSDS (1:200) on paraformaldehyde-fixed paraffin embedded mouse lung)

product-image-AAA13859_APP3.jpg Application Data (Immunoperoxidase of polyclonal antibody to CTSDS (1:200) on paraformaldehyde-fixed paraffin embedded mouse lung)

Application Data

product-image-AAA13859_APP2.jpg Application Data

Reactivity Chart

product-image-AAA13859_REACTIVITY.jpg Reactivity Chart
Related Product Information for anti-CTSD antibody
Cathepsin D

Goat polyclonal antibody to Cathepsin D. Cathepsin D is a lysosomal aspartic protease of the pepsin family. Acid protease active in intracellular protein breakdown. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
cathepsin D preproprotein
NCBI Official Synonym Full Names
cathepsin D
NCBI Official Symbol
CTSD
NCBI Official Synonym Symbols
CPSD; CLN10; HEL-S-130P
NCBI Protein Information
cathepsin D; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; epididymis secretory sperm binding protein Li 130P
UniProt Protein Name
Cathepsin D
UniProt Gene Name
CTSD
UniProt Synonym Gene Names
CPSD
UniProt Entry Name
CATD_HUMAN

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Product Notes

The CTSD ctsd (Catalog #AAA13859) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Cathepsin D Polyclonal Antibody reacts with Reacts against human, rat, mouse, canine and monkey proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Cathepsin D can be used in a range of immunoassay formats including, but not limited to, Western Blot, Immunofluorescence, Immunohistochemistry (paraffin), Immunohistochemistry (frozen), IEM. Western Blot: 1:250-1:1,000
Immunofluorescence 1:50-1:200
Immunohistochemistry (paraffin) 1:50-200
Immunohistochemistry (frozen) 1:50-1:200
IEM 1:50-1:200. Researchers should empirically determine the suitability of the CTSD ctsd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cathepsin D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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