Goat CAV1 / Caveolin 1 Polyclonal Antibody | anti-CAV1 antibody

Goat Polyclonal to Human CAV1 / Caveolin 1

Cat. Num. AAA50756

• Gene Names: CAV1; CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085
• Reactivity: Gibbon, Chimpanzee, Gorilla, Human, Monkey; Predicted Reactivity: Orangutan, Guinea pig (at least 90% immunogen sequence identity)
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: CAV1 / Caveolin 1, Antibody; Goat Polyclonal to Human CAV1 / Caveolin 1; Anti-CAV1 / Caveolin 1 Antibody (Internal) IHC-plus; CAV1; Caveolin-1; CGL3; CAV; MSTP085; VIP21; BSCL3; Human CAV1; Caveolin 1; anti-CAV1 antibody

• Host: Goat
• Reactivity: Gibbon, Chimpanzee, Gorilla, Human, Monkey; Predicted Reactivity: Orangutan, Guinea pig (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human CAV1 / Caveolin. No cross-reactivity expected to Caveolin 2 and Caveolin 3
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 178

• Applicable Applications for anti-CAV1 antibody: ELISA, WB (Western Blot), IHC (Immunohistochemistry)
• Target Species: Human
• Immunogen Description: Synthetic peptide C-DELSEKQVYDAH from an internal region of human CAV1 / Caveolin (NP_001744.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Marmoset (100%); Orangutan, Guinea pig (92%).
• Immunogen Type: Synthetic peptide
• Immunogen: CAV1 / Caveolin 1 antibody was raised against synthetic peptide C-DELSEKQVYDAH from an internal region of human CAV1 / Caveolin (NP_001744.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Marmoset (100%); Orangutan, Guinea pig (92%); Mouse, Rat, Dog, Bat, Hamster, Rabbit, Horse (83%).
• Antigen Modification: Internal
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

IHC (Immunohistochemistry)

(Anti-CAV1 / Caveolin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Related Product Information for anti-CAV1 antibody

Caveolin 1 (CAV1) is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 functions as a membrane adaptor to link integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 may also be a tumor suppressor gene and a negative regulator of the Ras-p42/44 MAP kinase cascade.

NCBI and Uniprot Product Information

• NCBI GI #: 15451856
• NCBI GeneID: 857
• NCBI Accession #: NP_001744.2
• NCBI GenBank Nucleotide #: NM_001753.4
• UniProt Accession #: Q03135; Q9UGP1; Q9UNG1; Q9UQH6
• Molecular Weight: 17,023 Da
• NCBI Official Full Name: caveolin-1 isoform alpha
• NCBI Official Synonym Full Names: caveolin 1, caveolae protein, 22kDa
• NCBI Official Symbol: CAV1
• NCBI Official Synonym Symbols: CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085
• NCBI Protein Information: caveolin-1; cell growth-inhibiting protein 32
• UniProt Protein Name: Caveolin-1
• UniProt Gene Name: CAV1
• UniProt Synonym Gene Names: CAV
• UniProt Entry Name: CAV1_HUMAN