WB (Western Blot)
(Detection of human CCDC88A by western blot. Samples: Whole cell lysate (50 ug) from HeLa and HEK293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CCDC88A antibody AAA212111 (lot AAA212111-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
Rabbit anti-Human CCDC88A Polyclonal Antibody | anti-CCDC88A antibody
Rabbit anti-CCDC88A Antibody, Affinity Purified
Gene Names
CCDC88A; APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
Reactivity
Human
Applications
Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
CCDC88A, Antibody; Rabbit anti-CCDC88A Antibody, Affinity Purified; GIRDIN; KIAA1212; PEHO; Hook-related protein 1; HkRP1; GRDN; GIV; girders of actin filament; g alpha-interacting vesicle-associated protein; Coiled-coil domain-containing protein 88A; APE; AKT-phosphorylation enhancer; Akt phosphorylation enhancer; PEHOL; girders of actin filaments; Girdin; coiled-coil domain containing 88A; anti-CCDC88A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-CCDC88A antibody
IP (Immunoprecipitation), WB (Western Blot)
Predicted Reactivity
Mouse
Immunogen
Between 1425 and 1475
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human CCDC88A by western blot. Samples: Whole cell lysate (50 ug) from HeLa and HEK293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CCDC88A antibody AAA212111 (lot AAA212111-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
WB (Western Blot)
(Detection of human CCDC88A by western blot. Samples: Whole cell lysate (50 ug) from HeLa and HEK293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CCDC88A antibody AAA212111 (lot AAA212111-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
IP (Immunoprecipitation)
(Detection of human CCDC88A by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-CCDC88A antibody AAA212111 (lot AAA212111-1) used for IP at 6 ug per reaction. CCDC88A was also immunoprecipitated by rabbit anti-CCDC88A antibody For blotting immunoprecipitated CCDC88A, AAA212111 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
IP (Immunoprecipitation)
(Detection of human CCDC88A by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-CCDC88A antibody AAA212111 (lot AAA212111-1) used for IP at 6 ug per reaction. CCDC88A was also immunoprecipitated by rabbit anti-CCDC88A antibody For blotting immunoprecipitated CCDC88A, AAA212111 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
Related Product Information for anti-CCDC88A antibody
CCDC88A encodes the protein known as GIV (G alpha-interacting vesicle-associated protein) and Girdin. CCDC88A plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. CCDC88A Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. CCDC88A has also been found to be essential for the integrity of the actin cytoskeleton and for cell migration. It is required for formation of actin stress fibers and lamellipodia, and it may be involved in membrane sorting in the early endosome [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q3V6T2].
Product Categories/Family for anti-CCDC88A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
216,042 Da
NCBI Official Full Name
girdin isoform 1
NCBI Official Synonym Full Names
coiled-coil domain containing 88A
NCBI Official Symbol
CCDC88A
NCBI Official Synonym Symbols
APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
NCBI Protein Information
girdin; Hook-related protein 1; girders of actin filament; girders of actin filaments; AKT-phosphorylation enhancer; g alpha-interacting vesicle-associated protein
UniProt Protein Name
Girdin
UniProt Gene Name
CCDC88A
UniProt Synonym Gene Names
APE; GRDN; KIAA1212; APE; GIV; HkRP1
UniProt Entry Name
GRDN_HUMAN
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Product Notes
The CCDC88A ccdc88a (Catalog #AAA212111) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-CCDC88A Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCDC88A can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the CCDC88A ccdc88a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCDC88A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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