IF (Immunofluorescence)
(Immunofluorescence of Girdin in human brain tissue with Girdin antibody at 20 μg/mL.)
Rabbit Girdin Polyclonal Antibody | anti-CCDC88A antibody
Girdin Antibody
Gene Names
CCDC88A; APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, ELISA
Purity
Girdin Antibody is affinity chromatography purified via peptide column.
Synonyms
Girdin, Antibody; Girdin Antibody; Girdin; APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212; Akt phosphorylation enhancer; coiled-coil domain containing 88A; anti-CCDC88A antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Girdin Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1843
Applicable Applications for anti-CCDC88A antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
Girdin antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus human Girdin.
Buffer
Girdin Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Girdin antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of Girdin in human brain tissue with Girdin antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of Girdin in human brain tissue with Girdin antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of Girdin in rat brain tissue lysate with Girdin antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of Girdin in rat brain tissue lysate with Girdin antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-CCDC88A antibody
Girdin Antibody: Girdin is a Galpha-interacting protein that can enhance the activation of the protein kinase Akt, remodel the actin cytoskeleton, and is thought to be involved in the regulation of cell migration and cancer metastasis. It has recently been shown that Girdin interacts with Disrupted-in-Schizophrenia 1 (DISC1), a susceptibility gene for major psychiatric disorders. DISC1 is thought to be involved in the migration, positioning and differentiation of dentate granule cells (DGCs) during development; depletion of Girdin or blocking the Girdin-DISC1 interaction results in defects in axonal sprouting in the CA3 region of the hippocampus and overextended migration of mispositioning of DGCs, suggesting the Girdin plays a role in postnatal neurogenesis in the dentate gyrus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
207,797 Da
NCBI Official Full Name
girdin isoform 2
NCBI Official Synonym Full Names
coiled-coil domain containing 88A
NCBI Official Symbol
CCDC88A
NCBI Official Synonym Symbols
APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
NCBI Protein Information
girdin; Hook-related protein 1; girders of actin filament; girders of actin filaments; AKT-phosphorylation enhancer; g alpha-interacting vesicle-associated protein
UniProt Protein Name
Girdin
UniProt Gene Name
CCDC88A
UniProt Synonym Gene Names
; APE; GIV; HkRP1
UniProt Entry Name
GRDN_HUMAN
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Product Notes
The CCDC88A ccdc88a (Catalog #AAA40160) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Girdin Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Girdin can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the CCDC88A ccdc88a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Girdin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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