IHC (Immunohiostchemistry)
(CCNB1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCNB1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit CCNB1 Polyclonal Antibody | anti-CCNB1 antibody
CCNB1 Antibody (Center)
Gene Names
CCNB1; CCNB
Reactivity
Reacts with: Human Predicted Reactivity: Bovine, Hamster, Mouse, Rat.
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CCNB1, Antibody; CCNB1 Antibody (Center); G2/mitotic-specific cyclin-B1; CCNB1; CCNB; anti-CCNB1 antibody
Host
Rabbit
Reactivity
Reacts with: Human
Predicted Reactivity: Bovine, Hamster, Mouse, Rat.
Predicted Reactivity: Bovine, Hamster, Mouse, Rat.
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CCNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-268 amino acids from the Central region of human CCNB1.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Sequence Positions
241-268
Sequence Length
433
Applicable Applications for anti-CCNB1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Function
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Cellular Location
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CCNB1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCNB1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(CCNB1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCNB1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(CCNB1 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CCNB1 antibody detected the CCNB1 protein (arrow).)
WB (Western Blot)
(CCNB1 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CCNB1 antibody detected the CCNB1 protein (arrow).)
Related Product Information for anti-CCNB1 antibody
The protein encoded by this gene is a regulatory protein
involved in mitosis. The gene product complexes with p34(cdc2) to
form the maturation-promoting factor (MPF). Two alternative
transcripts have been found, a constitutively expressed transcript
and a cell cycle-regulated transcript, that is expressed
predominantly during G2/M phase. The different transcripts result
from the use of alternate transcription initiation sites. [provided
by RefSeq].
involved in mitosis. The gene product complexes with p34(cdc2) to
form the maturation-promoting factor (MPF). Two alternative
transcripts have been found, a constitutively expressed transcript
and a cell cycle-regulated transcript, that is expressed
predominantly during G2/M phase. The different transcripts result
from the use of alternate transcription initiation sites. [provided
by RefSeq].
Product Categories/Family for anti-CCNB1 antibody
References
Kreis, N.N., et al. Oncogene 29(41):5591-5603(2010)
van Zon, W., et al. J. Cell Biol. 190(4):587-602(2010)
Harley, M.E., et al. EMBO J. 29(14):2407-2420(2010)
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Nantajit, D., et al. PLoS ONE 5 (8), E12341 (2010) :
van Zon, W., et al. J. Cell Biol. 190(4):587-602(2010)
Harley, M.E., et al. EMBO J. 29(14):2407-2420(2010)
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Nantajit, D., et al. PLoS ONE 5 (8), E12341 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48337
NCBI Official Full Name
G2/mitotic-specific cyclin-B1
NCBI Official Synonym Full Names
cyclin B1
NCBI Official Symbol
CCNB1
NCBI Official Synonym Symbols
CCNB
NCBI Protein Information
G2/mitotic-specific cyclin-B1
UniProt Protein Name
G2/mitotic-specific cyclin-B1
UniProt Gene Name
CCNB1
UniProt Synonym Gene Names
CCNB
UniProt Entry Name
CCNB1_HUMAN
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Product Notes
The CCNB1 ccnb1 (Catalog #AAA285884) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 241-268. The CCNB1 Antibody (Center) reacts with Reacts with: Human Predicted Reactivity: Bovine, Hamster, Mouse, Rat. and may cross-react with other species as described in the data sheet. AAA Biotech's CCNB1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CCNB1 ccnb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCNB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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