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product-image-AAA51580_AD10.jpg Transfection Control (HEK293 cells transfected with vector only)

Rabbit CCR7 Polyclonal Antibody | anti-CCR7 antibody

Rabbit Polyclonal to Human CCR7

Gene Names
CCR7; BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7
Reactivity
Bat, Gibbon, Bovine, Gorilla, Horse, Human, Monkey
Predicted Reactivity: Mouse, Rat, Dog, Hamster, Pig, Rabbit (at least 90% immunogen sequence identity)
Applications
Immunocytochemistry, Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
CCR7, Antibody; Rabbit Polyclonal to Human CCR7; Anti-CCR7 Antibody (C-Terminus) IHC-plus; CCR7; BLR2; Chemokine (C-C) receptor 7; CD197; C-C CKR-7; CMKBR7; CC chemokine receptor 7; CCR-7; CD197 antigen; CDw197; EBI1; EVI1; MIP-3 beta receptor; C-c chemokine receptor 7; C-C chemokine receptor type 7; CC-CKR-7; Chemokine c-c motif receptor 7; Human CCR7; anti-CCR7 antibody
Ordering
Host
Rabbit
Reactivity
Bat, Gibbon, Bovine, Gorilla, Horse, Human, Monkey
Predicted Reactivity: Mouse, Rat, Dog, Hamster, Pig, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human CCR7. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CXCR5 (65%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
378
Applicable Applications for anti-CCR7 antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from C-terminus of human CCR7. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bat, Bovine, Horse (100%); Mouse, Rat, Hamster, Elephant, Panda, Dog, Rabbit, Pig (94%).
Immunogen Type
Synthetic peptide
Immunogen
CCR7 antibody was raised against synthetic 17 amino acid peptide from C-terminus of human CCR7. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bat, Bovine, Horse (100%); Mouse, Rat, Hamster, Elephant, Panda, Dog, Rabbit, Pig (94%); Turkey, Chicken, Zebrafish (88%); Opossum, Xenopus, Pufferfish (82%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Transfection Control

(HEK293 cells transfected with vector only)

product-image-AAA51580_AD10.jpg Transfection Control (HEK293 cells transfected with vector only)

Transfection Control

(HEK293 expressing transfected CCR7)

product-image-AAA51580_AD11.jpg Transfection Control (HEK293 expressing transfected CCR7)

IHC (Immunohiostchemistry)

(Anti-CCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.)

product-image-AAA51580_IHC13.jpg IHC (Immunohiostchemistry) (Anti-CCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.)

IHC (Immunohistochemistry)

(Anti-CCR7 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.)

product-image-AAA51580_IHC15.jpg IHC (Immunohistochemistry) (Anti-CCR7 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.)
Related Product Information for anti-CCR7 antibody
CCR7, a Chemokine Receptor, is involved in lymphocyte recirculation through secondary lymphoid organs and moving lymphocytes and dendritic cells into distinct tissue compartments. CCR7 is called the Epstein-Barr-induced receptor because it mediates Epstein-Barr viral effects on B lymphocytes. CCR7 expression is up-regulated in mature dendritic cells, B cells infected with EBV, and in CD4+ cells infected with human herpes virus 6 and 7.
Product Categories/Family for anti-CCR7 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,874 Da
NCBI Official Full Name
C-C chemokine receptor type 7
NCBI Official Synonym Full Names
chemokine (C-C motif) receptor 7
NCBI Official Symbol
CCR7
NCBI Official Synonym Symbols
BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7
NCBI Protein Information
C-C chemokine receptor type 7; MIP-3 beta receptor; CC chemokine receptor 7; Bukitt's lymphoma receptor 2; Epstein-Barr virus induced gene 1; EBV-induced G protein-coupled receptor 1; lymphocyte-specific G protein-coupled peptide receptor; Epstein-Barr virus-induced G-protein coupled receptor 1
UniProt Protein Name
C-C chemokine receptor type 7
UniProt Gene Name
CCR7
UniProt Synonym Gene Names
CMKBR7; EBI1; EVI1; C-C CKR-7; CC-CKR-7; CCR-7; EBI1; EBV-induced G-protein coupled receptor 1
UniProt Entry Name
CCR7_HUMAN

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Product Notes

The CCR7 ccr7 (Catalog #AAA51580) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human CCR7 reacts with Bat, Gibbon, Bovine, Gorilla, Horse, Human, Monkey Predicted Reactivity: Mouse, Rat, Dog, Hamster, Pig, Rabbit (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's CCR7 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CCR7 ccr7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCR7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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