Application Data
(Paraffin embedded mouse spleen stained with Goat anti human CD284 (AAA50071))
Goat anti-Mouse, Rat CD284 Polyclonal Antibody | anti-CD284 antibody
GOAT ANTI HUMAN CD284 (N-TERMINAL)
Gene Names
TLR4; TOLL; CD284; TLR-4; ARMD10
Reactivity
Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Synonyms
CD284, Antibody; GOAT ANTI HUMAN CD284 (N-TERMINAL); anti-CD284 antibody
Host
Goat
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0mg/ml (varies by lot)
Sequence Length
799
Applicable Applications for anti-CD284 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Perservative Stabilisers
0.1% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin
0.1% Bovine Serum Albumin
Histology Positive Control Tissue
Spleen or tonsil
Buffer Solution
Buffer Solution
Antiserum Preparation
Antiserum to human CD284 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Paraffin embedded mouse spleen stained with Goat anti human CD284 (AAA50071))
Application Data
(Paraffin embedded mouse spleen stained with Goat anti human CD284 (AAA50071))
Application Data
(Paraffin embedded human tonsil stained with Goat anti human CD284 (AAA50071))
Application Data
(Paraffin embedded human tonsil stained with Goat anti human CD284 (AAA50071))
Related Product Information for anti-CD284 antibody
Goat anti Human CD284 antibody recognizes the human Toll-like receptor 4, also known as CD284, hToll or TLR4. CD284 is an 839 amino acid ~96 kDa single pass type I transmembrane glycoprotein expressed by peripheral blood leucocytes, activated T cells, monocytes, macrophages, dendritic cells, granulocytes and endothelial cells. CD284 plays a primary role in the activation of innate immunity (UniProt: O00206). Goat anti Human CD284 antibody recognizes an epitope within the N-terminal (NT) region of CD284, a highly conserved member of the toll-like receptor family which acts as a receptor for bacterial lipopolysaccharides (LPS) in co-operation with CD14 and MD2 (LY96), resulting in the activation of the MyD88-dependent and MyD88-independent (TRIF-dependent) signalling pathways and the production of inflammatory cytokines. LPS-activated CD284 can also induce dendritic cell maturation via TRIF-dependent signaling. Goat anti Human CD284 antibody is reported to be suitable for use in immunocytochemistry on acetone fixed cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
73,301 Da
NCBI Official Full Name
toll-like receptor 4 isoform C
NCBI Official Synonym Full Names
toll-like receptor 4
NCBI Official Symbol
TLR4
NCBI Official Synonym Symbols
TOLL; CD284; TLR-4; ARMD10
NCBI Protein Information
toll-like receptor 4; hToll; homolog of Drosophila toll
UniProt Protein Name
Toll-like receptor 4
UniProt Gene Name
TLR4
UniProt Entry Name
TLR4_HUMAN
Similar Products
CD284 Antibody
Host: Rabbit
Reactivity: Human, Mouse
Apps: ELISA, Immunohistochemistry, Western Blot
CD284 Antibody
Host: Rabbit
Reactivity: Human, Mouse
Apps: ELISA, Immunohistochemistry, Western Blot
Product Notes
The CD284 tlr4 (Catalog #AAA50071) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The GOAT ANTI HUMAN CD284 (N-TERMINAL) reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD284 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD284 tlr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD284, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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