IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain tissue using CD314 Polyclonal Antibody at dilution of 1:200.)
Rabbit anti-Human CD314 Polyclonal Antibody | anti-CD314 antibody
CD314 Polyclonal Antibody
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Affinity Purification
Synonyms
CD314, Antibody; CD314 Polyclonal Antibody; NKG2-D type II integral membrane protein (Killer cell lectin-like receptor subfamily K member 1) (NK cell receptor D) (NKG2-D-activating NK receptor) (CD antigen CD314); anti-CD314 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
216
Applicable Applications for anti-CD314 antibody
ELISA, IHC (Immunohistochemistry)
Immunogen
Synthetic peptide from human protein
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain tissue using CD314 Polyclonal Antibody at dilution of 1:200.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain tissue using CD314 Polyclonal Antibody at dilution of 1:200.)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human kidney tissue using CD314 Polyclonal Antibody at dilution of 1:200.)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human kidney tissue using CD314 Polyclonal Antibody at dilution of 1:200.)
Related Product Information for anti-CD314 antibody
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,274 Da
NCBI Official Full Name
NKG2-D type II integral membrane protein
NCBI Official Synonym Full Names
KLRC4-KLRK1 readthrough
NCBI Official Symbol
KLRC4-KLRK1
NCBI Protein Information
NKG2-D type II integral membrane protein
UniProt Protein Name
NKG2-D type II integral membrane protein
UniProt Gene Name
KLRK1
UniProt Synonym Gene Names
D12S2489E; NKG2D
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Product Notes
The CD314 klrk1 (Catalog #AAA173913) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD314 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD314 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD314 klrk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD314, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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