Rabbit anti-Human CD3E Polyclonal Antibody | anti-CD3E antibody

CD3E Rabbit anti-Human Polyclonal Antibody

Cat. Num. AAA162961

• Gene Names: CD3E; T3E; TCRE; IMD18
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Immunoaffinity purified
• Synonyms: CD3E, Antibody; CD3E Rabbit anti-Human Polyclonal Antibody; PathPlus CD3E Antibody; CD3E; CD3e antigen; CD3-epsilon; T-cell receptor epsilon chain; TCRE; T-cell receptors epsilon chain; T3E; CD3 Epsilon; CD3; anti-CD3E antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Immunoaffinity purified
• Form/Format: PBS, 0.1% Sodium Azide
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-CD3E antibody: IHC (Immunohistochemistry)
• Target: Human CD3E
• Immunogen: LP-10688, synthetic peptide
• Conjugation: Unconjugated
• Preparation and Storage: Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze-thaw cycles.

IHC (Immunohiostchemistry)

(CD3E Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))

IHC (Immunohistochemistry)

(CD3E Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))

Related Product Information for anti-CD3E antibody

CD3E antibody is an unconjugated rabbit polyclonal antibody to CD3E from human. Validated for IHC.
CD3e, epsilon (CD3E) is a polypeptide subunit of the T-cell receptor-CD3 complex, which plays an important role in T-cell development and the adaptive immune response. Along with its associated CD3 subunits, it couples activation of T-cell receptors by antigen-presenting cells to intracellular signal transduction pathways. Mutations in the CD3E gene cause immunodeficiency, and the gene may be linked to susceptibility to type 1 diabetes in women. CD3E is expressed in T cells and is found in the bone marrow and tissues of the immune system such as lymph node, spleen, appendix, and tonsil. CD3E antibodies are used to identify T cells in benign and malignant disorders.

References

Proc Natl Acad Sci USA. 1998;95(25):14909-14914. doi: 10.1073/pnas.95.25.14909. Nat Genet. 1993;3(1):77-81. doi: 10.1038/ng0193-77. J Clin Invest. 2004;114(10):1512-1517. doi: 10.1172/JCI22588. Clin Exp Immuno. 1991;83(1):69-73. doi: 10.1111/j.1365-2249.1991.tb05590.x.

NCBI and Uniprot Product Information

• NCBI GI #: 4502671
• NCBI GeneID: 916
• NCBI Accession #: NP_000724.1
• NCBI GenBank Nucleotide #: NM_000733
• UniProt Accession #: P07766; A8K997
• NCBI Official Full Name: T-cell surface glycoprotein CD3 epsilon chain
• NCBI Official Synonym Full Names: CD3e molecule, epsilon (CD3-TCR complex)
• NCBI Official Symbol: CD3E
• NCBI Official Synonym Symbols: T3E; TCRE; IMD18
• NCBI Protein Information: T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain
• UniProt Protein Name: T-cell surface glycoprotein CD3 epsilon chain
• UniProt Gene Name: CD3E
• UniProt Synonym Gene Names: T3E
• UniProt Entry Name: CD3E_HUMAN