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product-image-AAA52503_WB10.jpg WB (Western Blot) (Western blot of CDH3 Antibody (N-term) in NIH-3T3 cell line lysates (35 ug/lane). CDH3 (arrow) was detected using the purified Pab.)

Rabbit anti-Human, Mouse CDH3 / P-Cadherin Polyclonal Antibody | anti-CDH3 antibody

Rabbit Polyclonal to Human CDH3 / P-Cadherin

Gene Names
CDH3; CDHP; HJMD; PCAD
Reactivity
Human, Mouse
Applications
Flow Cytometry, Functional Assay, Western Blot, Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
CDH3 / P-Cadherin, Antibody; Rabbit Polyclonal to Human CDH3 / P-Cadherin; Anti-CDH3 / P-Cadherin Antibody (N-Terminus) IHC-plus; CDH3; Cadherin-3; HJMD; P-cadherin; CDHP; PCAD; Placental cadherin; Human CDH3; P-Cadherin; anti-CDH3 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS with 0.09% (w/v) sodium azide
Sequence Length
829
Applicable Applications for anti-CDH3 antibody
FCM/FACS (Flow Cytometry), WB (Western Blot), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic peptide located between amino acids 114 and 142 of P22223.
Immunogen
CDH3 / P-Cadherin antibody was raised against synthetic peptide located between amino acids 114 and 142 of P22223.
Antigen Modification
N-Terminus
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

WB (Western Blot)

(Western blot of CDH3 Antibody (N-term) in NIH-3T3 cell line lysates (35 ug/lane). CDH3 (arrow) was detected using the purified Pab.)

product-image-AAA52503_WB10.jpg WB (Western Blot) (Western blot of CDH3 Antibody (N-term) in NIH-3T3 cell line lysates (35 ug/lane). CDH3 (arrow) was detected using the purified Pab.)

FCM/FACS (Flow Cytometry)

(Flow cytometry of NCI-H292 cells using CDH3 Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

product-image-AAA52503_FCM11.jpg FCM/FACS (Flow Cytometry) (Flow cytometry of NCI-H292 cells using CDH3 Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

IHC (Immunohiostchemistry)

(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with CDH3 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.)

product-image-AAA52503_IHC13.jpg IHC (Immunohiostchemistry) (Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with CDH3 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.)

IHC (Immunohistochemistry)

(Anti-CDH3 / P-Cadherin antibody IHC staining of human pancreatic duct. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

product-image-AAA52503_IHC15.jpg IHC (Immunohistochemistry) (Anti-CDH3 / P-Cadherin antibody IHC staining of human pancreatic duct. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-CDH3 antibody
CDH3, a classical cadherin, is an integral membrane, calcium-dependent glycoprotein that mediates cell-cell interactions. The protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Alterations in the CDH3 gene have been linked to hypotrichosis with juvenile macular dystrophy (HJMD), and aberrant expression of CDH3 protein has been associated with several types of malignancies, including prostate and breast carcinomas.
Product Categories/Family for anti-CDH3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
86,552 Da
NCBI Official Full Name
cadherin-3 preproprotein
NCBI Official Synonym Full Names
cadherin 3, type 1, P-cadherin (placental)
NCBI Official Symbol
CDH3
NCBI Official Synonym Symbols
CDHP; HJMD; PCAD
NCBI Protein Information
cadherin-3; calcium-dependent adhesion protein, placental
UniProt Protein Name
Cadherin-3
UniProt Gene Name
CDH3
UniProt Synonym Gene Names
CDHP; P-cadherin
UniProt Entry Name
CADH3_HUMAN

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Product Notes

The CDH3 cdh3 (Catalog #AAA52503) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human CDH3 / P-Cadherin reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CDH3 / P-Cadherin can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CDH3 cdh3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDH3 / P-Cadherin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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