IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/30.)
Rabbit anti-Human CDK12 Polyclonal Antibody | anti-CDK12 antibody
CDK12 Antibody
Gene Names
CDK12; CRK7; CRKR; CRKRS
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
CDK12, Antibody; CDK12 Antibody; CRK7; CRKR; CRKRS; hCDK12; anti-CDK12 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total CDK12 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
3.1 mg/ml (varies by lot)
Sequence Length
1481
Applicable Applications for anti-CDK12 antibody
IHC (Immunohistochemistry)
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to residues near the C terminal of human cyclin-dependent kinase 12
Target Name
CDK12
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/30.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/30.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using at dilution 1/30.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using at dilution 1/30.)
Related Product Information for anti-CDK12 antibody
CrkRS (Cdc2-related kinase, arginine/serine-rich, also designated CRK7 and CRKR) is an ubiquitous protein that appears to localize to the nucleus and link transcription and splicing machinery. CrkRS belongs to the serine/threonine protein kinase family and Cdc2/Cdkx subfamily. CrkRS has extensive proline-rich regions that resemble SH3 and WW domain binding sites, and an RS domain that is characteristic of splicing factors. The protein kinase domain of CrkRS is 89% identical to the CHED protein kinase, also designated CDC2L5 and cell division cycle 2-like 5 (cholinesterase-related cell division controller), however outside the kinase domains the two proteins are unique. Cell cycle control kinases can phosphorylate proteins important for differentiation and apoptosis and provide connections between proliferation, differentiation, apoptosis, and neurocytoskeleton dynamics.
Product Categories/Family for anti-CDK12 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
141,449 Da
NCBI Official Full Name
cyclin-dependent kinase 12 isoform 2
NCBI Official Synonym Full Names
cyclin-dependent kinase 12
NCBI Official Symbol
CDK12
NCBI Official Synonym Symbols
CRK7; CRKR; CRKRS
NCBI Protein Information
cyclin-dependent kinase 12
UniProt Protein Name
Cyclin-dependent kinase 12
UniProt Gene Name
CDK12
UniProt Synonym Gene Names
CRK7; CRKRS; KIAA0904; CrkRS; CDC2-related protein kinase 7; hCDK12
UniProt Entry Name
CDK12_HUMAN
Similar Products
Product Notes
The CDK12 cdk12 (Catalog #AAA306910) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDK12 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDK12 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CDK12 cdk12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDK12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.