IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embeded human placenta using at dilution of 1:100.)
Rabbit anti-Human Charged multivesicular body protein 2a Polyclonal Antibody | anti-CHMP2A antibody
Charged multivesicular body protein 2a Polyclonal Antibody
Gene Names
CHMP2A; BC2; BC-2; VPS2; CHMP2; VPS2A
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Charged multivesicular body protein 2a, Antibody; Charged multivesicular body protein 2a Polyclonal Antibody; CHMP2A; anti-CHMP2A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total Charged multivesicular body protein 2a polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
222
Applicable Applications for anti-CHMP2A antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant Human Charged multivesicular body protein 2a protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embeded human placenta using at dilution of 1:100.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embeded human placenta using at dilution of 1:100.)
WB (Western Blot)
(All lanes: Charged multivesicular body protein 2a antibody at 2ug/ml)
WB (Western Blot)
(All lanes: Charged multivesicular body protein 2a antibody at 2ug/ml)
Related Product Information for anti-CHMP2A antibody
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.
Product Categories/Family for anti-CHMP2A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,104 Da
NCBI Official Full Name
charged multivesicular body protein 2a
NCBI Official Synonym Full Names
charged multivesicular body protein 2A
NCBI Official Symbol
CHMP2A
NCBI Official Synonym Symbols
BC2; BC-2; VPS2; CHMP2; VPS2A
NCBI Protein Information
charged multivesicular body protein 2a
UniProt Protein Name
Charged multivesicular body protein 2a
UniProt Gene Name
CHMP2A
UniProt Synonym Gene Names
BC2; CHMP2; CHMP2a; Vps2-1; hVps2-1
UniProt Entry Name
CHM2A_HUMAN
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Product Notes
The CHMP2A chmp2a (Catalog #AAA308443) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Charged multivesicular body protein 2a Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Charged multivesicular body protein 2a can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CHMP2A chmp2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Charged multivesicular body protein 2a, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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