WB (Western Blot)
(Western blot analysis of CHRM2 (arrow) using rabbit polyclonal CHRM2 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CHRM2 gene.)
Rabbit CHRM2 Polyclonal Antibody | anti-CHRM2 antibody
CHRM2 Antibody (Center)
Gene Names
CHRM2; HM2
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Pig, Rat)
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CHRM2, Antibody; CHRM2 Antibody (Center); Muscarinic acetylcholine receptor M2; CHRM2; anti-CHRM2 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Pig, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CHRM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-364 amino acids from the Central region of human CHRM2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
336-364
Sequence Length
466
Applicable Applications for anti-CHRM2 antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of CHRM2 (arrow) using rabbit polyclonal CHRM2 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CHRM2 gene.)
WB (Western Blot)
(Western blot analysis of CHRM2 (arrow) using rabbit polyclonal CHRM2 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CHRM2 gene.)
WB (Western Blot)
(CHRM2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CHRM2 antibody detected the CHRM2 protein (arrow).)
WB (Western Blot)
(CHRM2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CHRM2 antibody detected the CHRM2 protein (arrow).)
Related Product Information for anti-CHRM2 antibody
The muscarinic cholinergic receptors belong to a larger
family of G protein-coupled receptors. The functional diversity of
these receptors is defined by the binding of acetylcholine to these
receptors and includes cellular responses such as adenylate cyclase
inhibition, phosphoinositide degeneration, and potassium channel
mediation. Muscarinic receptors influence many effects of
acetylcholine in the central and peripheral nervous system. The
muscarinic cholinergic receptor 2 is involved in mediation of
bradycardia and a decrease in cardiac contractility. Multiple
alternatively spliced transcript variants have been described for
this gene.
family of G protein-coupled receptors. The functional diversity of
these receptors is defined by the binding of acetylcholine to these
receptors and includes cellular responses such as adenylate cyclase
inhibition, phosphoinositide degeneration, and potassium channel
mediation. Muscarinic receptors influence many effects of
acetylcholine in the central and peripheral nervous system. The
muscarinic cholinergic receptor 2 is involved in mediation of
bradycardia and a decrease in cardiac contractility. Multiple
alternatively spliced transcript variants have been described for
this gene.
Product Categories/Family for anti-CHRM2 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Cannon, D.M., et al. Mol. Psychiatry (2010) In press :
Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Cannon, D.M., et al. Mol. Psychiatry (2010) In press :
Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51715
NCBI Official Full Name
muscarinic acetylcholine receptor M2
NCBI Official Synonym Full Names
cholinergic receptor, muscarinic 2
NCBI Official Symbol
CHRM2
NCBI Official Synonym Symbols
HM2
NCBI Protein Information
muscarinic acetylcholine receptor M2
UniProt Protein Name
Muscarinic acetylcholine receptor M2
UniProt Gene Name
CHRM2
UniProt Entry Name
ACM2_HUMAN
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Product Notes
The CHRM2 chrm2 (Catalog #AAA285956) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 336-364. The CHRM2 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Mouse, Pig, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's CHRM2 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CHRM2 chrm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHRM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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