WB (Western Blot)
(the cell lysate derived from 80% confluence -A431 was immunoprobed by Rabbit anti-Claudin 2 (AAA71313) at 1:500. an immune-reactive band is observed around ~24kDa.)
Rabbit Claudin 2 Polyclonal Antibody | anti-CLDN2 antibody
Rabbit anti Claudin 2 Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purification
Synonyms
Claudin 2, Antibody; Rabbit anti Claudin 2 Polyclonal Antibody; CLDN2; anti-CLDN2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody only recognizes Claudin-2 protein. It cross-reacts with human, rat and mouse. Others not tested.
Purity/Purification
Affinity Purification
Form/Format
Supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Sequence Length
230
Applicable Applications for anti-CLDN2 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Preparation
A synthetic peptide from C-terminus of human claudin 2 protein.
Positive Control
A431, Skin tissue
Cellular Location
Cellular junction/gap
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20°C to -70°. The antibodies can be stored at 2-8°C for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
WB (Western Blot)
(the cell lysate derived from 80% confluence -A431 was immunoprobed by Rabbit anti-Claudin 2 (AAA71313) at 1:500. an immune-reactive band is observed around ~24kDa.)
WB (Western Blot)
(the cell lysate derived from 80% confluence -A431 was immunoprobed by Rabbit anti-Claudin 2 (AAA71313) at 1:500. an immune-reactive band is observed around ~24kDa.)
Related Product Information for anti-CLDN2 antibody
The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. The tight junctions are specialized regions of cell to cell contact. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans-membrane domains and two extracellular loops, make up tight junction strands. Different tissues exhibit different Claudin composition.
References
Hashizume A; Ueno T; Furuse M; Tsukita S; Nakanishi Y; Hieda Y (2004), Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn 231 (2), 425-431.
NCBI and Uniprot Product Information
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Product Notes
The CLDN2 cldn2 (Catalog #AAA71313) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Claudin 2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Claudin 2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CLDN2 cldn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Claudin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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