IHC (Immunohiostchemistry)
(Immunochemical staining of human CLEC12A in human placenta with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human CLEC12A Polyclonal Antibody | anti-CLEC12A antibody
CLEC12A Antibody, Rabbit PAb, Antigen Affinity Purified
Gene Names
CLEC12A; CLL1; MICL; CD371; CLL-1; DCAL-2
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Synonyms
CLEC12A, Antibody; CLEC12A Antibody, Rabbit PAb, Antigen Affinity Purified; Anti-CD303 Antibody; Anti-CD371 Antibody; Anti-CLECSF11 Antibody; Anti-CLECSF7 Antibody; Anti-CLL-1 Antibody; Anti-CLL1 Antibody; Anti-DCAL-2 Antibody; Anti-DLEC Antibody; Anti-HECL Antibody; Anti-MICL Antibody; Anti-PRO34150 Antibody; anti-CLEC12A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human CLEC12A
Applicable Applications for anti-CLEC12A antibody
IHC (Immunohistochemistry), ELISA
Preparation
Produced in rabbits immunized with purified, recombinant Human CLEC12A (rh CLEC12A;EAW96132.1; His75-Ala275). CLEC12A specific IgG was purified by Human CLEC12A affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Immunochemical staining of human CLEC12A in human placenta with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohiostchemistry)
(Immunochemical staining of human CLEC12A in human placenta with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human CLEC12A in human spleen with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human CLEC12A in human spleen with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-CLEC12A antibody
CLEC12A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. CLEC12A is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. C-type lectins are the most diverse and prevalent lectin family in immunity. Using a novel CLEC12A -specific monoclonal antibody, experiments had shown that human CLEC12A was expressed primarily on myeloid cells, including granulocytes, monocytes, macrophages, and dendritic cells. Although CLEC12A was highly N-glycosylated in primary cells, the level of glycosylation was found to vary between cell types. CLEC12A surface expression was down-regulated during inflammatory/activation conditions in vitro, as well as during an in vivo model of acute inflammation. This suggests that CLEC12A may be involved in the control of myeloid cell activation during inflammation.
Product Categories/Family for anti-CLEC12A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Mol_Mass: 26 kDa
AP_Mol_Mass: 40-45 kDa
AP_Mol_Mass: 40-45 kDa
NCBI Official Full Name
C-type lectin domain family 12, member A, isoform CRA_a
NCBI Official Synonym Full Names
C-type lectin domain family 12 member A
NCBI Official Symbol
CLEC12A
NCBI Official Synonym Symbols
CLL1; MICL; CD371; CLL-1; DCAL-2
NCBI Protein Information
C-type lectin domain family 12 member A
Similar Products
Product Notes
The CLEC12A (Catalog #AAA258633) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLEC12A Antibody, Rabbit PAb, Antigen Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLEC12A can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the CLEC12A for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLEC12A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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