WB (Western Blot)
(Western blot analysis of CLPB Antibody (C-term) in T47D cell line lysates (35ug/lane). CLPB (arrow) was detected using the purified Pab.)
Rabbit anti-Human CLPB Polyclonal Antibody | anti-CLPB antibody
CLPB Antibody (C-term)
Gene Names
CLPB; SKD3; HSP78; MGCA7; ANKCLB; MEGCANN
Reactivity
Human
Applications
ELISA, Western Blot
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Synonyms
CLPB, Antibody; CLPB Antibody (C-term); Caseinolytic peptidase B protein homolog; Suppressor of potassium transport defect 3; CLPB; HSP78; SKD3; anti-CLPB antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CLPB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 673-702 amino acids from the C-terminal region of human CLPB.
Purity/Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Positions
673-702
Sequence Length
506
Applicable Applications for anti-CLPB antibody
ELISA, WB (Western Blot)
Function
May function as a regulatory ATPase and be related to secretion/protein trafficking process. Involved in mitochondrial- mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and pro-inflammatory cytokine IL6 (PubMed:31522117).
Cellular Location
Mitochondrion intermembrane space
Tissue Location
Widely expressed (at protein level) (PubMed:25597511). Expressed in fetal, as well as in adult tissues, with highest levels in adult brain, including thalamus, hippocampus, occipital cortex and parietal cortex. Low expression in granulocytes (PubMed:25597510).
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of CLPB Antibody (C-term) in T47D cell line lysates (35ug/lane). CLPB (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of CLPB Antibody (C-term) in T47D cell line lysates (35ug/lane). CLPB (arrow) was detected using the purified Pab.)
Related Product Information for anti-CLPB antibody
CLPB may function as a regulatory ATPase and be related to secretion/protein trafficking process.
Product Categories/Family for anti-CLPB antibody
References
Acebron, S.P., et al. FEBS Lett. 583(18):2991-2996(2009)
Sowa, M.E., et al. Cell 138(2):389-403(2009)
Haslberger, T., et al. Nat. Struct. Mol. Biol. 15(6):641-650(2008)
Sowa, M.E., et al. Cell 138(2):389-403(2009)
Haslberger, T., et al. Nat. Struct. Mol. Biol. 15(6):641-650(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
78729
NCBI Official Full Name
caseinolytic peptidase B protein homolog isoform 2
NCBI Official Synonym Full Names
ClpB homolog, mitochondrial AAA ATPase chaperonin
NCBI Official Symbol
CLPB
NCBI Official Synonym Symbols
SKD3; HSP78; MGCA7; ANKCLB; MEGCANN
NCBI Protein Information
caseinolytic peptidase B protein homolog
UniProt Protein Name
Caseinolytic peptidase B protein homolog
UniProt Gene Name
CLPB
UniProt Synonym Gene Names
HSP78; SKD3
UniProt Entry Name
CLPB_HUMAN
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Product Notes
The CLPB clpb (Catalog #AAA289906) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 673-702. The CLPB Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLPB can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CLPB clpb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLPB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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