WB (Western Blot)
(Western blot analysis of extracts from HUVEC cells and HeLa cells, using CNOT7 antibody.)
Rabbit anti-Human, Mouse CNOT7 Polyclonal Antibody | anti-CNOT7 antibody
CNOT7 Antibody
Gene Names
CNOT7; CAF1; Caf1a; hCAF-1
Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CNOT7, Antibody; CNOT7 Antibody; BTG1 binding factor 1; BTG1-binding factor 1; CCR4-NOT transcription complex; 7; CCR4-associated factor 1; anti-CNOT7 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total CNOT7 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
285
Applicable Applications for anti-CNOT7 antibody
WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from N-terminal of human CNOT7.
Target Name
CNOT7
SDS-PAGE MW
36 kD
Preparation and Storage
Store at -20°C
WB (Western Blot)
(Western blot analysis of extracts from HUVEC cells and HeLa cells, using CNOT7 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from HUVEC cells and HeLa cells, using CNOT7 antibody.)
Related Product Information for anti-CNOT7 antibody
Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.Bogdan J.A., Biochem. J. 336:471-481(1998).The MGC Project Team; Genome Res. 14:2121-2127(2004).
Product Categories/Family for anti-CNOT7 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,228 Da
NCBI Official Full Name
CCR4-NOT transcription complex subunit 7 isoform 1
NCBI Official Synonym Full Names
CCR4-NOT transcription complex, subunit 7
NCBI Official Symbol
CNOT7
NCBI Official Synonym Symbols
CAF1; Caf1a; hCAF-1
NCBI Protein Information
CCR4-NOT transcription complex subunit 7
UniProt Protein Name
CCR4-NOT transcription complex subunit 7
UniProt Gene Name
CNOT7
UniProt Synonym Gene Names
CAF1; CAF-1
UniProt Entry Name
CNOT7_HUMAN
Similar Products
Product Notes
The CNOT7 cnot7 (Catalog #AAA305673) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNOT7 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CNOT7 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the CNOT7 cnot7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNOT7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.