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product-image-AAA288903_FCM11.jpg FCM/FACS (Flow Cytometry) (COG2 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Rabbit anti-Human COG2 Polyclonal Antibody | anti-COG2 antibody

COG2 Antibody (N-term)

Gene Names
COG2; LDLC
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
COG2, Antibody; COG2 Antibody (N-term); Conserved oligomeric Golgi complex subunit 2; COG complex subunit 2; Component of oligomeric Golgi complex 2; Low density lipoprotein receptor defect C-complementing protein; COG2; LDLC; anti-COG2 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This COG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the N-terminal region of human COG2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
96-124
Sequence Length
737
Applicable Applications for anti-COG2 antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

FCM/FACS (Flow Cytometry)

(COG2 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

product-image-AAA288903_FCM11.jpg FCM/FACS (Flow Cytometry) (COG2 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

IHC (Immunohiostchemistry)

(COG2 Antibody (N-term) (RB17913) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the COG2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

product-image-AAA288903_IHC13.jpg IHC (Immunohiostchemistry) (COG2 Antibody (N-term) (RB17913) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the COG2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(Western blot analysis of COG2 Antibody (N-term) in Hela cell line lysates (35ug/lane). COG2 (arrow) was detected using the purified Pab.)

product-image-AAA288903_WB15.jpg WB (Western Blot) (Western blot analysis of COG2 Antibody (N-term) in Hela cell line lysates (35ug/lane). COG2 (arrow) was detected using the purified Pab.)
Related Product Information for anti-COG2 antibody
COG2 encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes.
Product Categories/Family for anti-COG2 antibody
References
Edwards, T.L., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (5), 721-735 (2009)
Luke, M.M., et al. Stroke 40(2):363-368(2009)
Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008)
Sohda, M., et al. Traffic 8(3):270-284(2007)
Ungar, D., et al. Trends Cell Biol. 16(2):113-120(2006)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
83208
NCBI Official Full Name
conserved oligomeric Golgi complex subunit 2 isoform 2
NCBI Official Synonym Full Names
component of oligomeric golgi complex 2
NCBI Official Symbol
COG2
NCBI Official Synonym Symbols
LDLC
NCBI Protein Information
conserved oligomeric Golgi complex subunit 2
UniProt Protein Name
Conserved oligomeric Golgi complex subunit 2
UniProt Gene Name
COG2
UniProt Synonym Gene Names
LDLC; COG complex subunit 2
UniProt Entry Name
COG2_HUMAN

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Product Notes

The COG2 cog2 (Catalog #AAA288903) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 96-124. The COG2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's COG2 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the COG2 cog2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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