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product-image-AAA45496_WB8.jpg WB (Western Blot) (Anti-Collagen I antibody, AAA45496, Western blottingLane 1: Rat Lung Tissue LysateLane 2: Human Placenta Tissue LysateLane 3: Rat Testis Tissue Lysate)

Rabbit Collagen I Polyclonal Antibody | anti-COL1A1 antibody

Anti-Collagen I antibody

Gene Names
Col1a1; Cola1; Mov13; Cola-1; Mov-13; Col1a-1
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Collagen I, Antibody; Anti-Collagen I antibody; Collagen alpha-1(I) chain; collagen, type I, alpha 1; Alpha 1 type I collagen antibody; Alpha 2 type I collagen antibody; Alpha-1 type I collagen antibody; CO1A1_HUMAN antibody; COL1A1 antibody; COL1A2 antibody; Collagen alpha-1(I) chain antibody; Collagen I alpha 1 polypeptide antibody; Collagen I alpha 2 polypeptide antibody; Collagen Of Skin Tendon And Bone antibody; Collagen Type 1 antibody; Collagen type I alpha 1 antibody; Collagen type I alpha 2 antibody; OI4 antibody; Osteogenesis Imperfecta Type IV antibody; Pro alpha 1(I) collagen antibody; Type I procollagen antibody; anti-COL1A1 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4
Sequence Length
1453
Applicable Applications for anti-COL1A1 antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse COL1A1(1192-1207aa QPPQEKSQDGGRYYRA), identical to the related rat sequence, and different from the related human sequence by two amino acids.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Relevant Detection Systems
The lab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG ( ) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit ( ) for IHC(P), IHC(F) and ICC.
Preparation and Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

WB (Western Blot)

(Anti-Collagen I antibody, AAA45496, Western blottingLane 1: Rat Lung Tissue LysateLane 2: Human Placenta Tissue LysateLane 3: Rat Testis Tissue Lysate)

product-image-AAA45496_WB8.jpg WB (Western Blot) (Anti-Collagen I antibody, AAA45496, Western blottingLane 1: Rat Lung Tissue LysateLane 2: Human Placenta Tissue LysateLane 3: Rat Testis Tissue Lysate)

IHC (Immunohistochemistry)

(Anti-Collagen I antibody, AAA45496, IHC(F)IHC(F): Human Placenta Tissue)

product-image-AAA45496_IHC10.jpg IHC (Immunohistochemistry) (Anti-Collagen I antibody, AAA45496, IHC(F)IHC(F): Human Placenta Tissue)

ICC (Immunocytochemistry)

(Anti-Collagen I antibody, AAA45496, ICCICC: NIH3T3 Cell)

product-image-AAA45496_ICC11.jpg ICC (Immunocytochemistry) (Anti-Collagen I antibody, AAA45496, ICCICC: NIH3T3 Cell)

IHC (Immunohiostchemistry)

(Anti-Collagen I antibody, AAA45496, IHC(P)IHC(P): Human Intestinal Cancer Tissue)

product-image-AAA45496_IHC13.jpg IHC (Immunohiostchemistry) (Anti-Collagen I antibody, AAA45496, IHC(P)IHC(P): Human Intestinal Cancer Tissue)

IHC (Immunohistochemistry)

(Anti-Collagen I antibody, AAA45496, IHC(P)IHC(P): Rat Lung Tissue)

product-image-AAA45496_IHC15.jpg IHC (Immunohistochemistry) (Anti-Collagen I antibody, AAA45496, IHC(P)IHC(P): Rat Lung Tissue)
Related Product Information for anti-COL1A1 antibody
Background: Collagen, type I, alpha 1, also known as COL1A1, is a human gene that encodes the major component of type I collagen, the fibrillar collagen found in most connective tissues, including cartilage. This gene is mapped to 17q21.33. This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Collagen alpha-1(I) chain
NCBI Official Synonym Full Names
collagen, type I, alpha 1
NCBI Official Symbol
Col1a1
NCBI Official Synonym Symbols
Cola1; Mov13; Cola-1; Mov-13; Col1a-1
NCBI Protein Information
collagen alpha-1(I) chain; collagen alpha-1(I) chain; alpha-1 type 1 collagen; alpha-1 type I collagen; procollagen, type I, alpha 1
UniProt Protein Name
Collagen alpha-1(I) chain
UniProt Gene Name
Col1a1
UniProt Synonym Gene Names
Cola1
UniProt Entry Name
CO1A1_MOUSE

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Product Notes

The COL1A1 col1a1 (Catalog #AAA45496) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Collagen I antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Collagen I can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the COL1A1 col1a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Collagen I, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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