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product-image-AAA45744_IHC13.jpg IHC (Immunohiostchemistry) (Anti-Collagen IV Picoband antibody, AAA45744-2.JPGIHC(P): Human Lung Cancer Tissue)

Rabbit anti-Human Collagen IV Polyclonal Antibody | anti-COL4A1 antibody

Anti-Collagen IV Antibody

Gene Names
COL4A1; ICH; HANAC; POREN1; arresten
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Collagen IV, Antibody; Anti-Collagen IV Antibody; Collagen alpha-1(IV) chain; collagen, type IV, alpha 1; Arresten antibody; Canstatin antibody; CO4A1_HUMAN antibody; COL4A1 antibody; COL4A1 NC1 domain antibody; COL4A2 antibody; COL4A3 antibody; COL4A4 antibody; COL4A5 antibody; Collagen Alpha 1(IV) Chain antibody; Collagen Alpha 2(IV) Chain antibody; collagen alpha-1(IV) chain antibody; Collagen IV Alpha 1 Polypeptide antibody; Collagen IV Alpha 2 Polypeptide antibody; Collagen Of Basement Membrane Alpha 1 Chain antibody; Collagen Of Basement Membrane Alpha 2 Chain antibody; Collagen Type IV Alpha 1 antibody; Collagen Type IV Alpha 2 antibody; Collagen Type IV Alpha 3 antibody; Collagen Type IV Alpha 4 antibody; Collagen Type IV Alpha 5 antibody; DKFZp686I14213 antibody; FLJ22259 antibody; anti-COL4A1 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
1669
Applicable Applications for anti-COL4A1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
E Coli-derived human Collagen IV recombinant protein (Position: G1445-T1669). Human Collagen IV shares 97% amino acid (aa) sequence identity with mouse Collagen IV.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

IHC (Immunohiostchemistry)

(Anti-Collagen IV Picoband antibody, AAA45744-2.JPGIHC(P): Human Lung Cancer Tissue)

product-image-AAA45744_IHC13.jpg IHC (Immunohiostchemistry) (Anti-Collagen IV Picoband antibody, AAA45744-2.JPGIHC(P): Human Lung Cancer Tissue)

Application Data

(Anti-Collagen IV Picoband antibody, AAA45744-1.jpgAll lanes: Anti Collagen IV (AAA45744) at 0.5ug/mlWB: Recombinant Human Collagen IV Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD)

product-image-AAA45744_AD15.jpg Application Data (Anti-Collagen IV Picoband antibody, AAA45744-1.jpgAll lanes: Anti Collagen IV (AAA45744) at 0.5ug/mlWB: Recombinant Human Collagen IV Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD)
Related Product Information for anti-COL4A1 antibody
Description: Rabbit IgG polyclonal antibody for Collagen alpha-1(IV) chain(COL4A1) detection. Tested with WB, IHC-P in Human.
Background: COL4A1, also known as ICH or Collagen alpha-1(IV), is a protein that in humans is encoded by the COL4A1 gene. It is mapped to 13q34. This gene encodes the major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. COL4A1 binds to alpha-1/beta-1 integrin and inhibits migration, proliferation, and tube formation by endothelial cells. It is also a potential therapeutic candidate for targeting tumor angiogenesis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
127,981 Da
NCBI Official Full Name
Collagen alpha-1(IV) chain
NCBI Official Synonym Full Names
collagen, type IV, alpha 1
NCBI Official Symbol
COL4A1
NCBI Official Synonym Symbols
ICH; HANAC; POREN1; arresten
NCBI Protein Information
collagen alpha-1(IV) chain; collagen alpha-1(IV) chain; COL4A1 NC1 domain; collagen IV, alpha-1 polypeptide; collagen of basement membrane, alpha-1 chain
UniProt Protein Name
Collagen alpha-1(IV) chain
UniProt Gene Name
COL4A1
UniProt Entry Name
CO4A1_HUMAN

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Product Notes

The COL4A1 col4a1 (Catalog #AAA45744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Collagen IV Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Collagen IV can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the COL4A1 col4a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Collagen IV, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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