IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human pancreatic tissue using AAA229797 at dilution of 1:100)
Rabbit anti-Human, mouse COPB1 Polyclonal Antibody | anti-COPB1 antibody
COPB1 Antibody
Gene Names
COPB1; COPB
Reactivity
Human, mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity Purified
Synonyms
COPB1, Antibody; COPB1 Antibody; Coatomer subunit beta; COPB1; COPB; MSTP026; Beta-coat protein; Beta-COP; anti-COPB1 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
Liquid
Sequence Length
953
Applicable Applications for anti-COPB1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Recombinant human Coatomer subunit beta protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-13337 / sc-13335 / sc-30091
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human pancreatic tissue using AAA229797 at dilution of 1:100)
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human pancreatic tissue using AAA229797 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using AAA229797 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using AAA229797 at dilution of 1:100)
WB (Western Blot)
(Western blotAll lanes: COPB1 antibody at 1ug/mlLane 1: Hela whole cell lysateLane 2: Jurkat whole cell lysateLane 3: NIH/3T3 whole cell lysateLane 4: Mouse liver tissueLane 5: A549 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 107 kDaObserved band size: 107 kDa)
WB (Western Blot)
(Western blotAll lanes: COPB1 antibody at 1ug/mlLane 1: Hela whole cell lysateLane 2: Jurkat whole cell lysateLane 3: NIH/3T3 whole cell lysateLane 4: Mouse liver tissueLane 5: A549 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 107 kDaObserved band size: 107 kDa)
Related Product Information for anti-COPB1 antibody
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Plays a functional role in facilitating the transport of kappa-type opioid receptor mRNAs into axons and enhances translation of these proteins. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte surface triglyceride lipase (PNPLA2) with the lipid droplet to mediate lipolysis (By similarity). Involved in the Golgi disassembly and reassembly processes during cell cycle. Involved in autophagy by playing a role in early endosome function. Plays a role in organellar compartmentalization of secretory compartments including endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC), Golgi, trans-Golgi network (TGN) and recycling endosomes, and in biosynthetic transport of CAV1. Promotes degradation of Nef cellular targets CD4 and MHC class I antigens by facilitating their trafficking to degradative compartments.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
107,142 Da
NCBI Official Full Name
coatomer subunit beta
NCBI Official Synonym Full Names
coatomer protein complex subunit beta 1
NCBI Official Symbol
COPB1
NCBI Official Synonym Symbols
COPB
NCBI Protein Information
coatomer subunit beta
UniProt Protein Name
Coatomer subunit beta
UniProt Gene Name
COPB1
UniProt Synonym Gene Names
COPB; Beta-COP
UniProt Entry Name
COPB_HUMAN
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Product Notes
The COPB1 copb1 (Catalog #AAA229797) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The COPB1 Antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's COPB1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the COPB1 copb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COPB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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