CTBP2 Polyclonal Antibody | anti-CTBP2 antibody

Anti-CTBP2 Antibody

Cat. Num. AAA46574

• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Immunogen Affinity Purified
• Synonyms: CTBP2, Antibody; Anti-CTBP2 Antibody; C-terminal-binding protein 2; C terminal binding protein 2; CtBP2; CTBP2_HUMAN; ribeye antibody; C-terminal binding protein 2; anti-CTBP2 antibody

• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Purity/Purification: Immunogen Affinity Purified
• Form/Format: Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Sequence Length: 445

• Applicable Applications for anti-CTBP2 antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: E Coli-derived human CTBP2 recombinant protein (Position: H321-Q445). Human CTBP2 shares 99.2% and 98.4% amino acid (aa) sequence identity with mouse and rat CTBP2, respectively.
• Ig Type: Rabbit IgG
• Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
• Preparation and Storage: At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

IHC (Immunohistochemistry)

(Anti-CTBP2 Picoband antibody, AAA46574, IHC(P)IHC(P): Mouse Skeletal Muscle Tissue)

IHC (Immunohistochemisry)

(Anti-CTBP2 Picoband antibody, AAA46574, IHC(P)IHC(P): Rat Skeletal Muscle Tissue)

IHC (Immunohiostchemistry)

(Anti-CTBP2 Picoband antibody, AAA46574, IHC(P)IHC(P): Human Intestinal Cancer Tissue)

WB (Western Blot)

(Anti-CTBP2 Picoband antibody, AAA46574, Western blottingAll lanes: Anti CTBP2 (AAA46574) at 0.5ug/mlLane 1: COLO320 Whole Cell Lysate at 40ugLane 2: 293T Whole Cell Lysate at 40ugLane 3: HELA Whole Cell Lysate at 40ugPredicted bind size: 49KDObserved bind size: 49KD)

Related Product Information for anti-CTBP2 antibody

Description: Rabbit IgG polyclonal antibody for C-terminal-binding protein 2(CTBP2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Background: The E1a region of group C adenoviruses encodes 2 nearly identical proteins that are largely responsible for the oncogenic properties of adenoviruses. The CTBP1 protein binds to the C-terminal half of these E1A proteins. It's predicted that CTBP2 is a 445-amino acid protein and it is 72% identical to CTBP1. The CTBP2 gene is mapped to chromosome 10q26.13. CTBP2 is a mammalian corepressor that targets diverse transcriptional regulators. It bounds the short medial portion of delta-EF1 containing the PLDLSL motif and it enhances transrepression activity of delta-EF1.

References

1. Furusawa, T., Moribe, H., Kondoh, H., Higashi, Y.Identification of CtBP1 and CTBP2 as corepressors of zinc finger-homeodomain factor delta-EF1.Molec. Cell. Biol. 19: 8581-8590, 1999. 2. Thomas, G., Jacobs, K. B., Yeager, M., Kraft, P., Wacholder, S., Orr, N., Yu, K., Chatterjee, N., Welch, R., Hutchinson, A., Crenshaw, A., Cancel-Tassin, G., and 27 others.Multiple loci identified in a genome-wide association study of prostate cancer.Nature Genet. 40: 310-315, 2008. 3. Turner, J., Crossley, M.Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators.EMBO J. 17: 5129-5140, 1998.

NCBI and Uniprot Product Information

• NCBI GI #: 145580578
• NCBI GeneID: 1488
• NCBI Accession #: NP_001077383.1
• NCBI GenBank Nucleotide #: NM_001083914.2
• UniProt Accession #: P56545; O43449; Q5SQP7; Q69YI3; Q86SV0; Q9H2T8; A8K2X5; D3DRF5
• Molecular Weight: 106,187 Da
• NCBI Official Full Name: C-terminal-binding protein 2 isoform 1
• NCBI Official Synonym Full Names: C-terminal binding protein 2
• NCBI Official Symbol: CTBP2
• NCBI Protein Information: C-terminal-binding protein 2
• UniProt Protein Name: C-terminal-binding protein 2
• UniProt Gene Name: CTBP2
• UniProt Synonym Gene Names: CtBP2
• UniProt Entry Name: CTBP2_HUMAN