Rabbit anti-Human, Mouse CTBP2 Polyclonal Antibody | anti-CTBP2 antibody

CTBP2 antibody (pAb)

Cat. Num. AAA60001

• Reactivity: Human, Mouse
• Applications: Western Blot, Chromatin Immunoprecipitation, Immunoprecipitation, Chromatin Immunoprecipitation, Immunoprecipitation
• Purity: Affinity Purified
• Synonyms: CTBP2, Antibody; CTBP2 antibody (pAb); anti-CTBP2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purified
• Form/Format: Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

• Applicable Applications for anti-CTBP2 antibody: WB (Western Blot), ChIP (Chromatin immunoprecipitation), ChIP (Chromatin immunoprecipitation)
• Immunogen: This CTBP2 antibody was raised against a peptide in the C-terminal region of human CTBP2. This antibody recognizes both isoform 1 and 2.
• Preparation and Storage: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul

WB (Western Blot)

(CTBP2 antibody (pAb) tested by Western blot Nuclear extract of HeLa cells (10 ug) probed with CTBP2 antibody (1:1000).)

ChIP (Chromatin Immunoprecipitation)

(CTBP2 antibody (pAb) tested by ChIP-Seq. ChIP was performed using the ChIP-IT High Sensitivity Kit with 30 ug of chromatin from mouse liver and 10 ul of antibody. ChIP DNA was sequenced on the Illumina HiSeq and 15 million sequence tags were mapped to identify CTBP2 binding sites. The image shows binding across a regions of chromosome 11. You can view the complete data set in the UCSC Genome Browser)

Related Product Information for anti-CTBP2 antibody

Short Description: Our CTBP2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq and Western blot; it has been shown to react with Human and Mouse samples.

Background: The CTBP2 (C-terminal binding protein 2) gene encodes a protein that is a corepressor targeting diverse transcription regulators. It functions in brown adipose tissue (BAT) differentiation. Isoform 2 probably acts as a scaffold for specialized synapses. Isoform 2 is also phosphorylated upon DNA damage, probably by ATM or ATR at Thr179; Ser181 and Ser185. Phosphorylation by HIPK2 on Ser428 induces proteasomal degradation.

Product Categories/Family for anti-CTBP2 antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 145580578
• NCBI GeneID: 1488
• NCBI Accession #: NP_001077383; AB_2793573
• NCBI GenBank Nucleotide #: NM_001083914
• UniProt Accession #: P56545; O43449; Q5SQP7; Q69YI3; Q86SV0; Q9H2T8; A8K2X5; D3DRF5
• Molecular Weight: 106,187 Da
• NCBI Official Full Name: C-terminal-binding protein 2 isoform 1
• NCBI Official Synonym Full Names: C-terminal binding protein 2
• NCBI Official Symbol: CTBP2
• NCBI Protein Information: C-terminal-binding protein 2; ribeye
• UniProt Protein Name: C-terminal-binding protein 2
• UniProt Gene Name: CTBP2
• UniProt Synonym Gene Names: CtBP2
• UniProt Entry Name: CTBP2_HUMAN