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product-image-AAA324253_WB11.jpg WB (Western Blot) (Western blot analysis of extracts from Myeloma cells, using Cytochrome P450 1A2 Antibody. Lane 1 was treated with the antigen-specific peptide.)

Rabbit Cytochrome P450 1A2 Polyclonal Antibody | anti-CYP1A2 antibody

Cytochrome P450 1A2 Antibody

Gene Names
CYP1A2; CP12; CYPIA2; P3-450; P450(PA)
Reactivity
Human, Mouse, Rat
Purity
Peptide affinity purification
Synonyms
Cytochrome P450 1A2, Antibody; Cytochrome P450 1A2 Antibody; Aryl hydrocarbon hydroxylase; CP 12; CP12; CP1A2_HUMAN; CYP1A2; CYPIA2; Cytochrome P(3)450; Cytochrome P450 1A2; Cytochrome P450 4; Cytochrome P450 family 1 polypeptide 2; Cytochrome P450 family 1 subfamily A polypeptide 2; Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2; Cytochrome P450-P3; Cytochrome P4501A2; Dioxin inducable P3 450; Flavoprotein linked monooxygenase; Microsomal monooxygenase; P(3)450; P3 450; P450 4; P450 form 4; P450 P3; P450(PA); Xenobiotic monooxygenase; anti-CYP1A2 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Cytochrome P450 2E1 Antibody detects endogenous levels of total Cytochrome P450 2E1.
Purity/Purification
Peptide affinity purification
Form/Format
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Immunogen
A synthesized peptide derived from human Cytochrome P450 2E1, corresponding to a region within the internal amino acids.
Preparation and Storage
Store at -20°C. Stable for 12 months from date of receipt.

WB (Western Blot)

(Western blot analysis of extracts from Myeloma cells, using Cytochrome P450 1A2 Antibody. Lane 1 was treated with the antigen-specific peptide.)

product-image-AAA324253_WB11.jpg WB (Western Blot) (Western blot analysis of extracts from Myeloma cells, using Cytochrome P450 1A2 Antibody. Lane 1 was treated with the antigen-specific peptide.)

IHC (Immunohiostchemistry)

(AAA324253 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody at 4°C overnight. An HRP conjugated conjugated anti-rabbit Ab was used as secondary Ab)

product-image-AAA324253_IHC13.jpg IHC (Immunohiostchemistry) (AAA324253 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody at 4°C overnight. An HRP conjugated conjugated anti-rabbit Ab was used as secondary Ab)

WB (Western Blot)

(Western blot analysis of Cytochrome P450 1A2 Antibody expression in rat brain tissue lysates.The lane on the right is treated with the antigen-specific peptide.)

product-image-AAA324253_WB15.jpg WB (Western Blot) (Western blot analysis of Cytochrome P450 1A2 Antibody expression in rat brain tissue lysates.The lane on the right is treated with the antigen-specific peptide.)
Related Product Information for anti-CYP1A2 antibody
Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Similarity: Belongs to the cytochrome P450 family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
57 KD
NCBI Official Full Name
Cytochrome P450 1A2
NCBI Official Synonym Full Names
cytochrome P450 family 1 subfamily A member 2
NCBI Official Symbol
CYP1A2
NCBI Official Synonym Symbols
CP12; CYPIA2; P3-450; P450(PA)
NCBI Protein Information
cytochrome P450 1A2
UniProt Protein Name
Cytochrome P450 1A2
UniProt Gene Name
CYP1A2

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Product Notes

The CYP1A2 cyp1a2 (Catalog #AAA324253) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cytochrome P450 1A2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Cytochrome P450 1A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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