IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human kidney using AAA118610 at dilution 1:100)
Rabbit anti-Human Cytokine-inducible SH2-containing protein Polyclonal Antibody | anti-CISH antibody
Rabbit anti-human Cytokine-inducible SH2-containing protein polyclonal Antibody(CISH)
Gene Names
CISH; CIS; G18; SOCS; CIS-1; BACTS2
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purified
Synonyms
Cytokine-inducible SH2-containing protein, Antibody; Rabbit anti-human Cytokine-inducible SH2-containing protein polyclonal Antibody(CISH); CIS; CIS-1; Protein G18; Suppressor of cytokine signaling; SOCS; CISH; G18; anti-CISH antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
275
Applicable Applications for anti-CISH antibody
IHC (Immunohistochemistry), ELISA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Cytokine-inducible SH2-containing protein (1-257aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1529 / sc-1528 / sc-15344
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human kidney using AAA118610 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human kidney using AAA118610 at dilution 1:100)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human rectum using AAA118610 at dilution 1:100)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human rectum using AAA118610 at dilution 1:100)
Related Product Information for anti-CISH antibody
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,734 Da
NCBI Official Full Name
cytokine-inducible SH2-containing protein isoform 1
NCBI Official Synonym Full Names
cytokine inducible SH2-containing protein
NCBI Official Symbol
CISH
NCBI Official Synonym Symbols
CIS; G18; SOCS; CIS-1; BACTS2
NCBI Protein Information
cytokine-inducible SH2-containing protein
UniProt Protein Name
Cytokine-inducible SH2-containing protein
UniProt Gene Name
CISH
UniProt Synonym Gene Names
G18; CIS; SOCS
UniProt Entry Name
CISH_HUMAN
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Product Notes
The CISH cish (Catalog #AAA118610) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Cytokine-inducible SH2-containing protein polyclonal Antibody(CISH) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokine-inducible SH2-containing protein can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the CISH cish for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokine-inducible SH2-containing protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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