IHC (Immunohiostchemistry)
(DAZ3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DAZ3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human DAZ3 Polyclonal Antibody | anti-DAZ3 antibody
DAZ3 Antibody (C-term)
Gene Names
DAZ3; pDP1679
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
DAZ3, Antibody; DAZ3 Antibody (C-term); Deleted in azoospermia protein 3; DAZ3; anti-DAZ3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This DAZ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human DAZ3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
445-474
Sequence Length
438
Applicable Applications for anti-DAZ3 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(DAZ3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DAZ3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(DAZ3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DAZ3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(DAZ3 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DAZ3 antibody detected the DAZ3 protein (arrow).)
WB (Western Blot)
(DAZ3 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DAZ3 antibody detected the DAZ3 protein (arrow).)
Related Product Information for anti-DAZ3 antibody
This gene is a member of the DAZ gene family and is a
candidate for the human Y-chromosomal azoospermia factor (AZF). Its
expression is restricted to premeiotic germ cells, particularly in
spermatogonia. It encodes an RNA-binding protein that is important
for spermatogenesis. Four copies of this gene are found on
chromosome Y within palindromic duplications; one pair of genes is
part of the P2 palindrome and the second pair is part of the P1
palindrome. Each gene contains a 2.4 kb repeat including a 72-bp
exon, called the DAZ repeat; the number of DAZ repeats is variable
and there are several variations in the sequence of the DAZ repeat.
Each copy of the gene also contains a 10.8 kb region that may be
amplified; this region includes five exons that encode an RNA
recognition motif (RRM) domain. This gene contains one copy of the
10.8 kb repeat.
candidate for the human Y-chromosomal azoospermia factor (AZF). Its
expression is restricted to premeiotic germ cells, particularly in
spermatogonia. It encodes an RNA-binding protein that is important
for spermatogenesis. Four copies of this gene are found on
chromosome Y within palindromic duplications; one pair of genes is
part of the P2 palindrome and the second pair is part of the P1
palindrome. Each gene contains a 2.4 kb repeat including a 72-bp
exon, called the DAZ repeat; the number of DAZ repeats is variable
and there are several variations in the sequence of the DAZ repeat.
Each copy of the gene also contains a 10.8 kb region that may be
amplified; this region includes five exons that encode an RNA
recognition motif (RRM) domain. This gene contains one copy of the
10.8 kb repeat.
References
Kim, B., et al. Hum. Reprod. 24(6):1507-1515(2009)
Lardone, M.C., et al. Fertil. Steril. 88(5):1318-1326(2007)
A, Z.C., et al. Yi Chuan 28(9):1057-1060(2006)
Kuo, P.L., et al. Fertil. Steril. 81(4):1034-1040(2004)
Ferlin, A., et al. Fertil. Steril. 81(4):1013-1018(2004)
Lardone, M.C., et al. Fertil. Steril. 88(5):1318-1326(2007)
A, Z.C., et al. Yi Chuan 28(9):1057-1060(2006)
Kuo, P.L., et al. Fertil. Steril. 81(4):1034-1040(2004)
Ferlin, A., et al. Fertil. Steril. 81(4):1013-1018(2004)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54989
NCBI Official Full Name
deleted in azoospermia protein 3
NCBI Official Synonym Full Names
deleted in azoospermia 3
NCBI Official Symbol
DAZ3
NCBI Official Synonym Symbols
pDP1679
NCBI Protein Information
deleted in azoospermia protein 3
UniProt Protein Name
Deleted in azoospermia protein 3
UniProt Gene Name
DAZ3
UniProt Entry Name
DAZ3_HUMAN
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Product Notes
The DAZ3 daz3 (Catalog #AAA287461) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 445-474. The DAZ3 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DAZ3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the DAZ3 daz3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DAZ3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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