Rabbit DcR2 Polyclonal Antibody | anti-TNFRSF10D antibody

DcR2 Antibody

Cat. Num. AAA40371

• Gene Names: TNFRSF10D; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4
• Reactivity: Human, Mouse, Rat
• Applications: Immunocytochemistry, Western Blot, ELISA
• Purity: DcR2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: DcR2, Antibody; DcR2 Antibody; DcR2; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4; UNQ251/PRO288; Tumor necrosis factor receptor superfamily member 10D; Decoy receptor 2; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; anti-TNFRSF10D antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: DcR2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Sequence Length: 386

• Applicable Applications for anti-TNFRSF10D antibody: ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: DcR2 antibody was raised against a 15 amino acid peptide near the center of human DcR2.
• Buffer: DcR2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: DcR2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of DcR2 in mouse kidney tissue withDcR2 antibody at 20 μg/ml.Green: DcR2 Antibody (2021)Blue: DAPI staining)

IHC (Immunohistochemisry)

(Immunohistochemistry of DcR2 in mouse kidney node tissue with DcR2 antibody at 2.5 μg/ml.)

ICC (Immunocytochemistry)

(Immunocytochemistry staining of HeLa cells using DcR2 antibody at 10μg/mL.)

WB (Western Blot)

(Western blot analysis of DcR2 in HeLa whole cell lysate with DcR2 antibody at 1 μg/mL.)

Related Product Information for anti-TNFRSF10D antibody

DcR2 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis.

NCBI and Uniprot Product Information

• NCBI GI #: 18203495
• NCBI GeneID: 8793
• UniProt Accession #: Q9UBN6; Q9Y6Q4; B2R8W0
• Molecular Weight: 41,823 Da
• NCBI Official Full Name: Tumor necrosis factor receptor superfamily member 10D
• NCBI Official Synonym Full Names: tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
• NCBI Official Symbol: TNFRSF10D
• NCBI Official Synonym Symbols: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4
• NCBI Protein Information: tumor necrosis factor receptor superfamily member 10D; TRAIL receptor 4; decoy receptor 2; TNF receptor-related receptor for TRAIL; TRAIL receptor with a truncated death domain; TNF-related apoptosis-inducing ligand receptor 4
• UniProt Protein Name: Tumor necrosis factor receptor superfamily member 10D
• UniProt Gene Name: TNFRSF10D
• UniProt Synonym Gene Names: DCR2; TRAILR4; TRUNDD; DcR2; TRAIL receptor 4; TRAIL-R4
• UniProt Entry Name: TR10D_HUMAN