Rabbit anti-Mouse, Human DDR2 Polyclonal Antibody | anti-DDR2 antibody

DDR2 Rabbit anti-Human Polyclonal Antibody

Cat. Num. AAA162901

• Gene Names: DDR2; TKT; MIG20a; NTRKR3; TYRO10
• Reactivity: Mouse, Human
• Applications: Western Blot, Immunohistochemistry, Immunohistochemistry, Immunofluorescence, ELISA
• Purity: Protein G purified
• Synonyms: DDR2, Antibody; DDR2 Rabbit anti-Human Polyclonal Antibody; IHC-plus DDR2 Antibody; DDR2; CD167b antigen; Discoidin domain receptor 2; Hydroxyaryl-protein kinase; MIG20a; Tyrosine-protein kinase TYRO10; NTRKR3; TYRO10; Tyrosylprotein kinase; anti-DDR2 antibody

• Host: Rabbit
• Reactivity: Mouse, Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.
• Purity/Purification: Protein G purified
• Form/Format: PBS, pH7.4, 0.03% Proclin 300, 50% glycerol
• Concentration: 3.44mg/ml (varies by lot)

• Applicable Applications for anti-DDR2 antibody: WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA
• Target: Human DDR2
• Immunogen: Recombinant Human Discoidin domain-containing receptor 2 protein (447-540AA)
• Conjugation: Unconjugated
• Family: Protein Kinase
• Subfamily: DDR/TKT
• Preparation and Storage: Short term: store at -20 degree C. Long term: store at -80 degree C. Avoid freeze-thaw cycles.

IHC (Immunohistochemistry)

(DDR2 Antibody-Immunohistochemistry of paraffin-embedded human heart tissue using DDR2 Antibody at dilution of 1:100)

IHC (Immunohistochemisry)

(DDR2 Antibody-Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.)

WB (Western Blot)

(DDR2 Antibody-Positive WB detected in:Hela whole cell lysate,Jurkat whole cell lysate,HEK293 whole cell lysate,NIH/3T3 whole cell lysate,A549 whole cell lysate;All lanes:DDR2 antibody at 3.5?g/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 97 KDa;Observed band size: 97 KDa;)

ICC (Immunocytochemistry)

(DDR2 Antibody-Immunofluorescent analysis of HepG2 cells using DDR2 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-DDR2 antibody

DDR2 antibody is an unconjugated rabbit polyclonal antibody to DDR2 from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues.

NCBI and Uniprot Product Information

• NCBI GI #: 62420884
• NCBI GeneID: 4921
• NCBI Accession #: NP_006173.2
• NCBI GenBank Nucleotide #: NM_006182
• UniProt Accession #: Q16832; Q7Z730
• Molecular Weight: 96,736 Da
• NCBI Official Full Name: discoidin domain-containing receptor 2
• NCBI Official Synonym Full Names: discoidin domain receptor tyrosine kinase 2
• NCBI Official Symbol: DDR2
• NCBI Official Synonym Symbols: TKT; MIG20a; NTRKR3; TYRO10
• NCBI Protein Information: discoidin domain-containing receptor 2; tyrosylprotein kinase; hydroxyaryl-protein kinase; discoidin domain receptor 2; tyrosine-protein kinase TYRO10; CD167 antigen-like family member B; cell migration-inducing protein 20; migration-inducing gene 16 prot
• UniProt Protein Name: Discoidin domain-containing receptor 2
• UniProt Gene Name: DDR2
• UniProt Synonym Gene Names: NTRKR3; TKT; TYRO10; Discoidin domain receptor 2
• UniProt Entry Name: DDR2_HUMAN