IF (Immunofluorescence)
(Immunofluorescence of DISC1 in HeLa cells with DISC1 antibody at 20 μg/mL.)
Rabbit anti-Human, Mouse DISC1 Polyclonal Antibody | anti-DISC1 antibody
DISC1 Antibody
Gene Names
DISC1; SCZD9; C1orf136
Reactivity
Human, Mouse
Applications
Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
Purity
DISC1 Antibody is affinity chromatography purified via peptide column.
Synonyms
DISC1, Antibody; DISC1 Antibody; DISC1; SCZD9; C1orf136; KIAA0457; Disrupted in schizophrenia 1 protein; disrupted in schizophrenia 1; anti-DISC1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
DISC1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
854
Applicable Applications for anti-DISC1 antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
DISC1 antibody was raised against a 18 amino acid synthetic peptide from near the center of human DISC1.
Buffer
DISC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
DISC1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of DISC1 in HeLa cells with DISC1 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of DISC1 in HeLa cells with DISC1 antibody at 20 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of DISC1 in HeLa cells with DISC1 antibody at 5 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of DISC1 in HeLa cells with DISC1 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of DISC1 in SK-N-SH cell lysate with DISC1 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of DISC1 in SK-N-SH cell lysate with DISC1 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.)
Related Product Information for anti-DISC1 antibody
DISC1 Antibody: Disrupted in schizophrenia 1 (DISC1) is a candidate gene for susceptibility to schizophrenia. It was discovered through chromosomal analysis of a large Scottish family whose members exhibited schizophrenia and related psychiatric disorders. Through yeast two-hybrid screening, it was discovered that DISC1 interacts with many members of the centrosome and cytoskeletal system including MAP1A and Nudel. More recently, DISC1 has been found to regulate the transport of a complex containing Nudel, the lissencephaly-1 (LIS1) protein, and 14-3-3epsilon from neuronal cell bodies to the axons by the action of the microtubule-dependent directed motor protein kinesin-1, also known as KIF5A. Decreased expression of DISC1 in neurons caused an accelerated rate of neuronal integration, resulting in aberrant morphological development, suggesting that DISC1 plays a role in dendritic development and synapse formation. DISC1 has at least four known isoforms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,198 Da
NCBI Official Full Name
disrupted in schizophrenia 1 protein isoform L
NCBI Official Synonym Full Names
disrupted in schizophrenia 1
NCBI Official Symbol
DISC1
NCBI Official Synonym Symbols
SCZD9; C1orf136
NCBI Protein Information
disrupted in schizophrenia 1 protein
UniProt Protein Name
Disrupted in schizophrenia 1 protein
UniProt Gene Name
DISC1
UniProt Synonym Gene Names
KIAA0457
UniProt Entry Name
DISC1_HUMAN
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Product Notes
The DISC1 disc1 (Catalog #AAA40074) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DISC1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DISC1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the DISC1 disc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DISC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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