Application Data
(Immunocytochemical staining of HeLa cells with Rabbit anti Human DISC1 (AAA50013))
Rabbit anti-Mouse DISC1 Polyclonal Antibody | anti-DISC1 antibody
RABBIT ANTI DISC1
Gene Names
DISC1; SCZD9; C1orf136
Reactivity
Mouse
Applications
Western Blot, Immunohistochemistry
Synonyms
DISC1, Antibody; RABBIT ANTI DISC1; anti-DISC1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
This item recognises disrupted in schizophrenia 1 (DISC1), 93kD protein located in the nucleus, cytoplasm and mitochondria. The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE-like (NUDEL) and phosphodiesterase 4B.
In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1;11) (q42.1;q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition.This product has been found suitable for immunocytochemistry (ICC) at a concentration of 5ug/ml.
In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1;11) (q42.1;q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition.This product has been found suitable for immunocytochemistry (ICC) at a concentration of 5ug/ml.
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
832
Applicable Applications for anti-DISC1 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Perservative Stabilisers
0.02% Sodium Azide
Preparation
Preparation
Immunogen
An 18 amino acid peptide located near the centre of human DISC1.
Buffer Solution
Buffer Solution
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Immunocytochemical staining of HeLa cells with Rabbit anti Human DISC1 (AAA50013))
Application Data
(Immunocytochemical staining of HeLa cells with Rabbit anti Human DISC1 (AAA50013))
Application Data
(Western blot analysis of whole cell lysate from SK-N-SH human neuroblastoma cells probed with Rabbit anti Human DISC1 (AAA50013) at 0.5(A), 1(B) and 2(C) ug/ml)
Application Data
(Western blot analysis of whole cell lysate from SK-N-SH human neuroblastoma cells probed with Rabbit anti Human DISC1 (AAA50013) at 0.5(A), 1(B) and 2(C) ug/ml)
Related Product Information for anti-DISC1 antibody
MBS222900 recognises disrupted in schizophrenia 1 (DISC1), 93kD protein located in the nucleus, cytoplasm and mitochondria. The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE-like (NUDEL) and phosphodiesterase 4B. In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1;11) (q42.1;q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition. This product has been found suitable for immunocytochemistry (ICC) at a concentration of 5ug/ml.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,198 Da
NCBI Official Full Name
disrupted in schizophrenia 1 protein isoform Lv
NCBI Official Synonym Full Names
disrupted in schizophrenia 1
NCBI Official Symbol
DISC1
NCBI Official Synonym Symbols
SCZD9; C1orf136
NCBI Protein Information
disrupted in schizophrenia 1 protein
UniProt Protein Name
Disrupted in schizophrenia 1 protein
UniProt Gene Name
DISC1
UniProt Synonym Gene Names
KIAA0457
UniProt Entry Name
DISC1_HUMAN
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Product Notes
The DISC1 disc1 (Catalog #AAA50013) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI DISC1 reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DISC1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the DISC1 disc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DISC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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