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product-image-AAA40700_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of DNAJC13 in human heart tissue with DNAJC13 antibody at 5 μg/mL.)

Rabbit anti-Human, Mouse DNAJC13 Polyclonal Antibody | anti-DNAJC13 antibody

DNAJC13 Antibody

Gene Names
DNAJC13; RME8
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
DNAJC13 antibody is affinity chromatography purified via peptide column.
Synonyms
DNAJC13, Antibody; DNAJC13 Antibody; DNAJ homolog subfamily C member 13; receptor-mediated endocytosis 8; RME8; DnaJ (Hsp40) homolog, subfamily C, member 13; anti-DNAJC13 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
DNAJC13 antibody is human and mouse reactive. At least two siforms of DNAJC13 are known to exist; this antibody will detect both isoforms. DNAJC13 antibody is predicted to not cross-react with other DNAJC family members.
Purity/Purification
DNAJC13 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid; DNAJC13 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration
1 mg/mL (varies by lot)
Sequence Length
2243
Applicable Applications for anti-DNAJC13 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
DNAJC13 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DNAJC13.
The immunogen is located within amino acids 1940 - 1990 of DNAJC13.
Positive Control
1) - Human Heart Tissue Lysate
2) - Human Heart Tissue Slide
Preparation and Storage
DNAJC13 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

IHC (Immunohiostchemistry)

(Immunohistochemistry of DNAJC13 in human heart tissue with DNAJC13 antibody at 5 μg/mL.)

product-image-AAA40700_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of DNAJC13 in human heart tissue with DNAJC13 antibody at 5 μg/mL.)

WB (Western Blot)

(DNAJC13 Antibody.)

product-image-AAA40700_WB15.jpg WB (Western Blot) (DNAJC13 Antibody.)
Related Product Information for anti-DNAJC13 antibody
DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans (1). It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles (2). DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor (3).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 249 kDa

Observed: 249 kDa
NCBI Official Full Name
dnaJ homolog subfamily C member 13
NCBI Official Synonym Full Names
DnaJ (Hsp40) homolog, subfamily C, member 13
NCBI Official Symbol
DNAJC13
NCBI Official Synonym Symbols
RME8
NCBI Protein Information
dnaJ homolog subfamily C member 13; RME-8; DnaJ domain-containing protein RME-8; required for receptor-mediated endocytosis 8
UniProt Protein Name
DnaJ homolog subfamily C member 13
UniProt Gene Name
DNAJC13
UniProt Synonym Gene Names
KIAA0678; RME8; RME-8
UniProt Entry Name
DJC13_HUMAN

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Product Notes

The DNAJC13 dnajc13 (Catalog #AAA40700) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DNAJC13 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DNAJC13 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the DNAJC13 dnajc13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNAJC13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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