IHC (Immunohiostchemistry)
(Immunohistochemistry of DNaseII in human spleen tissue with DNaseII antibody at 5 ug/mL.)
Rabbit anti-Human DNase II Polyclonal Antibody | anti-DNase II antibody
DNase II Antibody
Gene Names
DNASE2; DNL; DNL2; DNASE2A
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
DNase II, Antibody; DNase II Antibody; DNase II; anti-DNase II antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1920
Applicable Applications for anti-DNase II antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a peptide corresponding to amino acids 347 to 360 of human DNase II precursor (2-4).
Target Name
DNase II
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of DNaseII in human spleen tissue with DNaseII antibody at 5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of DNaseII in human spleen tissue with DNaseII antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of DNase II in human spleen tissue lysate in the absence (lane 1) or presence (lane 2) of blocking peptide with DNase antibody II at 1:500 dilution.)
WB (Western Blot)
(Western blot analysis of DNase II in human spleen tissue lysate in the absence (lane 1) or presence (lane 2) of blocking peptide with DNase antibody II at 1:500 dilution.)
Related Product Information for anti-DNase II antibody
Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins including AIF and Acinus. DNase II causes both chromatin condensation and DNA fragmentation. The genes encoding human, porcine, and murine DNase II have been cloned. The DNase II gene encodes a 40 kDa proenzyme. The mature enzyme consists of two non-identical subunits, the 32 kDa (alpha) and 12 kDa (beta) chains, generated by proteolytic processing. Overexpression of DNase II induces chromatin condensation. DNase II is ubiquitously expressed in human tissues.
Product Categories/Family for anti-DNase II antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
33,615 Da
NCBI Official Full Name
Homo sapiens deoxyribonuclease II alpha mRNA, complete cds
NCBI Official Synonym Full Names
deoxyribonuclease II, lysosomal
NCBI Official Symbol
DNASE2
NCBI Official Synonym Symbols
DNL; DNL2; DNASE2A
NCBI Protein Information
deoxyribonuclease-2-alpha
UniProt Protein Name
Deoxyribonuclease-2-alpha
UniProt Gene Name
DNASE2
UniProt Synonym Gene Names
DNASE2A; DNL2; DNase II alpha
UniProt Entry Name
DNS2A_HUMAN
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Product Notes
The DNase II dnase2 (Catalog #AAA307504) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DNase II Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DNase II can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the DNase II dnase2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNase II, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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