WB (Western Blot)
(Figure 1. Western blot analysis of Drd4 using anti-Drd4 antibody.)
Rabbit anti-Mouse, Rat DRD4 Polyclonal Antibody | anti-Drd4 antibody
Anti-DRD4 Antibody
Gene Names
Drd4; D4R; Drd-4; AW125663
Reactivity
Mouse, Rat
Applications
ELISA, Flow Cytometry, Functional Assay, Western Blot
Purity
Immunogen affinity purified.
Synonyms
DRD4, Antibody; Anti-DRD4 Antibody; D(4) dopamine receptor; D(2C) dopamine receptor; Dopamine D4 receptor; Drd4; anti-Drd4 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
387
Applicable Applications for anti-Drd4 antibody
ELISA (Direct ELISA), FCM/FACS (Flow Cytometry), WB (Western Blot)
Immunogen
E Coli-derived mouse DRD4 recombinant protein (Position: A57-C387).
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen store at -20 degree C for a longer time. Avoid repeated freezing and thawing.
WB (Western Blot)
(Figure 1. Western blot analysis of Drd4 using anti-Drd4 antibody.)
WB (Western Blot)
(Figure 1. Western blot analysis of Drd4 using anti-Drd4 antibody.)
FCM/FACS (Flow Cytometry)
FCM/FACS (Flow Cytometry)
Related Product Information for anti-Drd4 antibody
Description: Rabbit IgG polyclonal antibody for DRD4 detection. Tested with WB, FCM, Direct ELISA in Mouse; Rat.
Background: D(4) dopamine receptor is a protein that in humans is encoded by the Drd4 gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
Background: D(4) dopamine receptor is a protein that in humans is encoded by the Drd4 gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
References
1. D'Souza, U. M., Russ, C., Tahir, E., Mill, J., McGuffin, P., Asherson, P. J., Craig, I. W. Functional effects of a tandem duplication polymorphism in the 5-prime flanking region of the DRD4 gene. Biol. Psychiat. 56: 691-697, 2004.
2. De Luca, A., Rizzardi, M., Buccino, A., Alessandroni, R., Salvioli, G. P., Filograsso, N., Novelli, G., Dallapiccola, B. Association of dopamine D4 receptor (DRD4) exon III repeat polymorphism with temperament in 3-year-old infants. Neurogenetics 4: 207-212, 2003.
3. De Luca, A., Rizzardi, M., Torrente, I., Alessandroni, R., Salvioli, G. P., Filograsso, N., Dallapiccola, B., Novelli, G. Dopamine D4 receptor (DRD4) polymorphism and adaptability trait during infancy: a longitudinal study in 1- to 5-month-old neonates. Neurogenetics 3: 79-82, 2001.
2. De Luca, A., Rizzardi, M., Buccino, A., Alessandroni, R., Salvioli, G. P., Filograsso, N., Novelli, G., Dallapiccola, B. Association of dopamine D4 receptor (DRD4) exon III repeat polymorphism with temperament in 3-year-old infants. Neurogenetics 4: 207-212, 2003.
3. De Luca, A., Rizzardi, M., Torrente, I., Alessandroni, R., Salvioli, G. P., Filograsso, N., Dallapiccola, B., Novelli, G. Dopamine D4 receptor (DRD4) polymorphism and adaptability trait during infancy: a longitudinal study in 1- to 5-month-old neonates. Neurogenetics 3: 79-82, 2001.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
D(4) dopamine receptor
NCBI Official Synonym Full Names
dopamine receptor D4
NCBI Official Symbol
Drd4
NCBI Official Synonym Symbols
D4R; Drd-4; AW125663
NCBI Protein Information
D(4) dopamine receptor
UniProt Protein Name
D(4) dopamine receptor
UniProt Gene Name
Drd4
UniProt Entry Name
DRD4_MOUSE
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Product Notes
The Drd4 drd4 (Catalog #AAA125412) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-DRD4 Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DRD4 can be used in a range of immunoassay formats including, but not limited to, ELISA (Direct ELISA), FCM/FACS (Flow Cytometry), WB (Western Blot). Researchers should empirically determine the suitability of the Drd4 drd4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DRD4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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