WB (Western Blot)
Rabbit DUSP6/MKP3 Polyclonal Antibody | anti-DUSP6/MKP3 antibody
DUSP6/MKP3 Rabbit pAb
Gene Names
DUSP6; MKP3; PYST1
Applications
Immunoprecipitation, Flow Cytometry, Functional Assay, Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Affinity purified
Synonyms
DUSP6/MKP3, Antibody; DUSP6/MKP3 Rabbit pAb; DUSP6;MKP3;PYST1;Dual specificity protein phosphatase 6;Dual specificity protein phosphatase PYST1;Mitogen-activated protein kinase phosphatase 3;MAP kinase phosphatase3;MKP-3; anti-DUSP6/MKP3 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
DUSP6 Rabbit Polyclonal detects endogenous levels of DUSP6
Purity/Purification
Affinity purified
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applicable Applications for anti-DUSP6/MKP3 antibody
IP (Immunoprecipitation), FCM/FACS (Flow Cytometry), IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide of human DUSP6
Subcellular Location
Cytoplasm
Preparation and Storage
Store at -15°C to -25°C/1 year (not lower than -25°C).
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-DUSP6/MKP3 antibody
Background:The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in t Function:catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Inactivates MAP kinases. Has a specificity for the ERK family.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.
Product Categories/Family for anti-DUSP6/MKP3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed Band(KD):42,44kD
NCBI Official Full Name
dual specificity protein phosphatase 6 isoform a
NCBI Official Synonym Full Names
dual specificity phosphatase 6
NCBI Official Symbol
DUSP6
NCBI Official Synonym Symbols
MKP3; PYST1
NCBI Protein Information
dual specificity protein phosphatase 6; MAP kinase phosphatase 3; dual specificity protein phosphatase PYST1; serine/threonine specific protein phosphatase; mitogen-activated protein kinase phosphatase 3
UniProt Protein Name
Dual specificity protein phosphatase 6
UniProt Gene Name
DUSP6
UniProt Synonym Gene Names
MKP3; PYST1; MAP kinase phosphatase 3; MKP-3
UniProt Entry Name
DUS6_HUMAN
Similar Products
Product Notes
The DUSP6/MKP3 dusp6 (Catalog #AAA268958) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DUSP6/MKP3 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), FCM/FACS (Flow Cytometry), IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the DUSP6/MKP3 dusp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DUSP6/MKP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.