IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using DUT Polyclonal Antibody at dilution 1:20)
Rabbit DUT Polyclonal Antibody | anti-DUT antibody
DUT Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Antigen affinity purification
Synonyms
DUT, Antibody; DUT Polyclonal Antibody; dUTPase; anti-DUT antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
0.7mg/mL (varies by lot)
Sequence Length
139
Applicable Applications for anti-DUT antibody
IHC (Immunohistochemistry), ELISA
Immunogen
Synthetic peptide of human DUT
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using DUT Polyclonal Antibody at dilution 1:20)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using DUT Polyclonal Antibody at dilution 1:20)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using DUT Polyclonal Antibody at dilution 1:20)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using DUT Polyclonal Antibody at dilution 1:20)
Related Product Information for anti-DUT antibody
This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15,195 Da
NCBI Official Full Name
DUT
NCBI Official Symbol
dut
NCBI Protein Information
dUTPase, putative; DUT
UniProt Protein Name
DUT
UniProt Gene Name
dut
UniProt Entry Name
Q77K24_9CAUD
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Product Notes
The DUT dut (Catalog #AAA168546) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DUT Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DUT can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the DUT dut for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DUT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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