IF (Immunofluorescence)
(Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using DCTN1 antibody (Green) at 1: 500 dilution and alpha-tubulin antibody (Red) at 1: 2000.)
Rabbit anti-Human dynactin 1 Polyclonal Antibody | anti-DCTN1 antibody
dynactin 1 antibody
Gene Names
DCTN1; P135; DP-150; DAP-150
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Purified by antigen-affinity chromatography.
Synonyms
dynactin 1, Antibody; dynactin 1 antibody; anti-DCTN1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 1XPBS, 1%BSA, 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Sequence Length
1278
Applicable Applications for anti-DCTN1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide contain a sequence corresponding to a region within amino acids 1216 and 1278 of dynactin 1
Target Name
dynactin 1
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.
IF (Immunofluorescence)
(Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using DCTN1 antibody (Green) at 1: 500 dilution and alpha-tubulin antibody (Red) at 1: 2000.)
IF (Immunofluorescence)
(Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using DCTN1 antibody (Green) at 1: 500 dilution and alpha-tubulin antibody (Red) at 1: 2000.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded OVCA, using dynactin 1 antibody at 1: 100 dilution.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded OVCA, using dynactin 1 antibody at 1: 100 dilution.)
Application Data
(Sample (30 ug of whole cell lysate) A: JurKat 5% SDS PAGE Primary antibody diluted at 1: 3000)
Application Data
(Sample (30 ug of whole cell lysate) A: JurKat 5% SDS PAGE Primary antibody diluted at 1: 3000)
Related Product Information for anti-DCTN1 antibody
This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). [provided by RefSeq]
Product Categories/Family for anti-DCTN1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
140,887 Da
NCBI Official Full Name
dynactin subunit 1 isoform 1
NCBI Official Synonym Full Names
dynactin 1
NCBI Official Symbol
DCTN1
NCBI Official Synonym Symbols
P135; DP-150; DAP-150
NCBI Protein Information
dynactin subunit 1
UniProt Protein Name
Dynactin subunit 1
UniProt Gene Name
DCTN1
UniProt Synonym Gene Names
DP-150
UniProt Entry Name
DCTN1_HUMAN
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Product Notes
The DCTN1 dctn1 (Catalog #AAA307284) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The dynactin 1 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's dynactin 1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the DCTN1 dctn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "dynactin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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