Rabbit anti-Human EPHA10 Polyclonal Antibody | anti-NEIL3 antibody
EPHA10 Conjugated Antibody
Gene Names
NEIL3; FGP2; FPG2; NEI3; hFPG2; hNEI3
Reactivity
Human
Purity
This antibody was affinity-purified from rabbit aniserum by affinity-chromatography using epitope-specific immunogen
Synonyms
EPHA10, Antibody; EPHA10 Conjugated Antibody; Endonuclease VIII-like 3; Nei-like 3; DNA glycosylase FPG2; anti-NEIL3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total NEIL3 protein.
Purity/Purification
This antibody was affinity-purified from rabbit aniserum by affinity-chromatography using epitope-specific immunogen
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Immunogen
Synthesized peptide derived from internal of human NEIL3.
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF750: 749nm/775nm
Preparation and Storage
Store at 4 degrees C in dark for 6 months.
Related Product Information for anti-NEIL3 antibody
DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA- (apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
68
NCBI Official Full Name
endonuclease 8-like 3
NCBI Official Synonym Full Names
nei endonuclease VIII-like 3 (E. coli)
NCBI Official Symbol
NEIL3
NCBI Official Synonym Symbols
FGP2; FPG2; NEI3; hFPG2; hNEI3
NCBI Protein Information
endonuclease 8-like 3; nei-like protein 3; DNA glycosylase FPG2; DNA glycosylase hFPG2; endonuclease VIII-like 3; DNA glycosylase/AP lyase Neil3
UniProt Protein Name
Endonuclease 8-like 3
UniProt Gene Name
NEIL3
UniProt Entry Name
NEIL3_HUMAN
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Product Notes
The NEIL3 neil3 (Catalog #AAA312756) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EPHA10 Conjugated Antibody reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "EPHA10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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