WB (Western Blot)
(Anti- ERVW-1 Picoband antibody, AAA46305, Western blottingAll lanes: Anti ERVW-1 (AAA46305) at 0.5ug/mlLane 1: Mouse Testis Tissue Lysate at 50ugLane 2: COLO320 Whole Cell Lysate at 40ugLane 3: 22RV1 Whole Cell Lysate at 40ugPredicted bind size: 60KDObserved bind size: 39KD)
ERVW-1 Polyclonal Antibody | anti-ERVW-1 antibody
Anti-ERVW-1 Antibody
Gene Names
ERVW-1; ENV; ENVW; HERVW; ERVWE1; HERV7Q; HERV-7q; HERVWENV; HERV-W-ENV
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Immunogen Affinity Purified
Synonyms
ERVW-1, Antibody; Anti-ERVW-1 Antibody; Syncytin-1; Endogenous retrovirus group W member 1; ENV; Envelope polyprotein gPr73; Enverin; ENVW; ERVWE1; HERV-7q; HERV-7q Envelope protein; HERV-W envelope protein; HERV-W-ENV; HERV-W_7q21.2 provirus ancestral Env polyprotein; HERV7Q; HERVW; HERVWENV; Syncytin 1; Syncytin; Syncytin1; endogenous retrovirus group W, member 1; anti-ERVW-1 antibody
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
No cross reactivity with other proteins
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
538
Applicable Applications for anti-ERVW-1 antibody
WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human ERVW-1 (406-435aa YYVNQSGIVTEKVKEIRDRIQRRAEELRNT).
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti- ERVW-1 Picoband antibody, AAA46305, Western blottingAll lanes: Anti ERVW-1 (AAA46305) at 0.5ug/mlLane 1: Mouse Testis Tissue Lysate at 50ugLane 2: COLO320 Whole Cell Lysate at 40ugLane 3: 22RV1 Whole Cell Lysate at 40ugPredicted bind size: 60KDObserved bind size: 39KD)
WB (Western Blot)
(Anti- ERVW-1 Picoband antibody, AAA46305, Western blottingAll lanes: Anti ERVW-1 (AAA46305) at 0.5ug/mlLane 1: Mouse Testis Tissue Lysate at 50ugLane 2: COLO320 Whole Cell Lysate at 40ugLane 3: 22RV1 Whole Cell Lysate at 40ugPredicted bind size: 60KDObserved bind size: 39KD)
Related Product Information for anti-ERVW-1 antibody
Description: Rabbit IgG polyclonal antibody for Syncytin-1(ERVW-1) detection. Tested with WB in Human;Mouse;Rat.
Background: ERVW-1 is also known as ERVWE1. The human ERVWE1 locus is derived from a human endogenous retrovirus-W (HERV-W) provirus located on chromosome 7. This provirus has inactivating mutations in the gag and pol genes, but the envelope glycoprotein gene has been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
Background: ERVW-1 is also known as ERVWE1. The human ERVWE1 locus is derived from a human endogenous retrovirus-W (HERV-W) provirus located on chromosome 7. This provirus has inactivating mutations in the gag and pol genes, but the envelope glycoprotein gene has been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
References
1. "Entrez Gene: ERVWE1 endogenous retroviral family W, env(C7), member 1 (syncytin)". 2. Li F, Nellåker C, Sabunciyan S, Yolken RH, Jones-Brando L, Johansson AS, Owe-Larsson B, Karlsson H. "Transcriptional derepression of the ERVWE1 locus following influenza A virus infection." J Virol, 2014 Apr.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
syncytin-1
NCBI Official Synonym Full Names
endogenous retrovirus group W member 1
NCBI Official Symbol
ERVW-1
NCBI Official Synonym Symbols
ENV; ENVW; HERVW; ERVWE1; HERV7Q; HERV-7q; HERVWENV; HERV-W-ENV
NCBI Protein Information
syncytin-1
UniProt Protein Name
Syncytin-1
UniProt Gene Name
ERVW-1
UniProt Synonym Gene Names
ERVWE1; SU; TM
UniProt Entry Name
SYCY1_HUMAN
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Product Notes
The ERVW-1 ervw-1 (Catalog #AAA46305) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-ERVW-1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ERVW-1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the ERVW-1 ervw-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ERVW-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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