WB (Western Blot)
(Detection of human EXOSC2 by western blot. Samples: Whole cell lysate from HEK293T (15 and 50 ug), HeLa (50ug), and Jurkat (50ug) cells. Antibodies: Affinity purified rabbit anti-EXOSC2 antibody AAA212347 (lot AAA212347-1) used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
Rabbit anti-Human, Mouse EXOSC2 Polyclonal Antibody | anti-EXOSC2 antibody
Rabbit anti-EXOSC2 Antibody, Affinity Purified
Gene Names
EXOSC2; p7; RRP4; Rrp4p; hRrp4p
Reactivity
Human, Mouse
Applications
Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
EXOSC2, Antibody; Rabbit anti-EXOSC2 Antibody, Affinity Purified; p7; exosome complex exonuclease RRP4; SHRF; Rrp4p; RRP4; ribosomal RNA-processing protein 4; hRrp4p; homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; Exosome component 2; exosome complex component RRP4; homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); Exosome complex component RRP4; exosome component 2; anti-EXOSC2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-EXOSC2 antibody
IP (Immunoprecipitation), WB (Western Blot)
Predicted Reactivity
Bovine
Immunogen
Between 243 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human EXOSC2 by western blot. Samples: Whole cell lysate from HEK293T (15 and 50 ug), HeLa (50ug), and Jurkat (50ug) cells. Antibodies: Affinity purified rabbit anti-EXOSC2 antibody AAA212347 (lot AAA212347-1) used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
WB (Western Blot)
(Detection of human EXOSC2 by western blot. Samples: Whole cell lysate from HEK293T (15 and 50 ug), HeLa (50ug), and Jurkat (50ug) cells. Antibodies: Affinity purified rabbit anti-EXOSC2 antibody AAA212347 (lot AAA212347-1) used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
WB (Western Blot)
(Detection of mouse EXOSC2 by western blot. Samples: Whole cell lysate (15 and 50 ug) from mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-EXOSC2 antibody AAA212347 (lot AAA212347-1) used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
WB (Western Blot)
(Detection of mouse EXOSC2 by western blot. Samples: Whole cell lysate (15 and 50 ug) from mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-EXOSC2 antibody AAA212347 (lot AAA212347-1) used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
IP (Immunoprecipitation)
(Detection of human EXOSC2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-EXOSC2 antibody AAA212347 (lot AAA212347-1) used for IP at 6 ug/mg lysate. EXOSC2 was also immunoprecipitated by rabbit anti-EXOSC2 antibody BL14001. For blotting immunoprecipitated EXOSC2, AAA212347 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
IP (Immunoprecipitation)
(Detection of human EXOSC2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-EXOSC2 antibody AAA212347 (lot AAA212347-1) used for IP at 6 ug/mg lysate. EXOSC2 was also immunoprecipitated by rabbit anti-EXOSC2 antibody BL14001. For blotting immunoprecipitated EXOSC2, AAA212347 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
Related Product Information for anti-EXOSC2 antibody
EXOSC2 is a non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13868].
Product Categories/Family for anti-EXOSC2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,045 Da
NCBI Official Full Name
Homo sapiens exosome component 2 (EXOSC2), transcript variant 1, mRNA
NCBI Official Synonym Full Names
exosome component 2
NCBI Official Symbol
EXOSC2
NCBI Official Synonym Symbols
p7; RRP4; Rrp4p; hRrp4p
NCBI Protein Information
exosome complex component RRP4; exosome complex exonuclease RRP4; homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; ribosomal RNA-processing protein
UniProt Protein Name
Exosome complex component RRP4
UniProt Gene Name
EXOSC2
UniProt Synonym Gene Names
RRP4
UniProt Entry Name
EXOS2_HUMAN
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Product Notes
The EXOSC2 exosc2 (Catalog #AAA212347) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-EXOSC2 Antibody, Affinity Purified reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's EXOSC2 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the EXOSC2 exosc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EXOSC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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