Application Data
Ezrin Polyclonal Antibody | anti-EZR antibody
Ezrin (Phospho-Tyr353)
Gene Names
EZR; CVL; CVIL; VIL2; HEL-S-105
Applications
Immunohistochemistry, Immunoblot, Western Blot
Synonyms
Ezrin, Antibody; Ezrin (Phospho-Tyr353); anti-EZR antibody
Clonality
Polyclonal
Specificity
This antibody detects endogenous human Ezrin only when phosphorylated at tyrosine 353.
Form/Format
100ul at 1.0mg/ml in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Affinity-purified on phosphopeptide; non-phosphopeptide- reactive antibodies were removed by chromatography on non-phosphorylated peptide.
Sequence Length
586
Applicable Applications for anti-EZR antibody
IHC (Immunohistochemistry), IB (Immunoblot)
Antigen
Peptide sequence that includes phosphorylation site of tyrosine 353 (Q-D-Y(p)-E-E) derived from human Ezrin and conjugated to KLH.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Can be stored at 4 degree C for short-term.
Application Data
Application Data
IHC (Immunohistochemistry)
IHC (Immunohistochemistry)
Related Product Information for anti-EZR antibody
Ezrin (also known as cytovillin or villin-2) is encoded by the EZR gene. The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. It plays a key role in cell surface structure adhesion, migration, and organization. The N-terminal FERM domain strongly binds sodium-hydrogen exchanger regulatory factor (NHERF) proteins (involving long-range allostery). The C-terminal ERM domain binds to actin, phosphatidylinositol(4,5)bis-phosphate (PIP2) and membrane proteins like CD44 and ICAM-2.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,413 Da
NCBI Official Full Name
ezrin
NCBI Official Synonym Full Names
ezrin
NCBI Official Symbol
EZR
NCBI Official Synonym Symbols
CVL; CVIL; VIL2; HEL-S-105
NCBI Protein Information
ezrin
UniProt Protein Name
Ezrin
UniProt Gene Name
EZR
UniProt Synonym Gene Names
VIL2
Similar Products
Product Notes
The EZR ezr (Catalog #AAA47838) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Ezrin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IB (Immunoblot). Researchers should empirically determine the suitability of the EZR ezr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ezrin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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