IF (Immunofluorescence)
(Immunofluorescence of FAM193B in Jurkat cells with FAM193B antibody at 20 μg/mL.)
Rabbit anti-Human FAM193B Polyclonal Antibody | anti-FAM193B antibody
FAM193B Antibody
Gene Names
FAM193B; IRIZIO
Reactivity
Human
Applications
Immunofluorescence, Western Blot, ELISA
Purity
FAM193B Antibody is affinity chromatography purified via peptide column.
Synonyms
FAM193B, Antibody; FAM193B Antibody; FAM193B; IRIZIO; KIAA1931; Protein FAM193B; family with sequence similarity 193, member B; anti-FAM193B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
At least two isoforms of FAM193B are known to exist; this antibody will detect both isoforms.
Purity/Purification
FAM193B Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
902
Applicable Applications for anti-FAM193B antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
FAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B.
Buffer
FAM193B Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
FAM193B antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of FAM193B in Jurkat cells with FAM193B antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of FAM193B in Jurkat cells with FAM193B antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of FAM193B in Jurkat cell lysate with FAM193B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of FAM193B in Jurkat cell lysate with FAM193B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-FAM193B antibody
FAM193B Antibody: FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
99 kDa
NCBI Official Full Name
Protein FAM193B
NCBI Official Synonym Full Names
family with sequence similarity 193, member B
NCBI Official Symbol
FAM193B
NCBI Official Synonym Symbols
IRIZIO
NCBI Protein Information
protein FAM193B
UniProt Protein Name
Protein FAM193B
UniProt Gene Name
FAM193B
UniProt Synonym Gene Names
IRIZIO; KIAA1931
UniProt Entry Name
F193B_HUMAN
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Product Notes
The FAM193B fam193b (Catalog #AAA40623) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FAM193B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FAM193B can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the FAM193B fam193b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FAM193B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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