Rabbit Fibulin 3 Polyclonal Antibody | anti-EFEMP1 antibody

Fibulin 3 Antibody

Cat. Num. AAA39692

• Gene Names: EFEMP1; DHRD; DRAD; FBNL; MLVT; MTLV; S1-5; FBLN3; FIBL-3
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: Fibulin 3 Antibody is affinity chromatography purified via peptide column.
• Synonyms: Fibulin 3, Antibody; Fibulin 3 Antibody; Fibulin 3; DHRD; DRAD; FBNL; MLVT; MTLV; S1-5; FBLN3; FIBL-3; EGF-containing fibulin-like extracellular matrix protein 1; Extracellular protein S1-5; anti-EFEMP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least three isoforms of Fibulin 3 are known to exist. This antibody is predicted to not cross-react with other Fibulin proteins.
• Purity/Purification: Fibulin 3 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 355

• Applicable Applications for anti-EFEMP1 antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Fibulin 3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human Fibulin 3.
• Buffer: Fibulin 3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: Fibulin 3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of Fibulin 3 in HeLa cells with Fibulin 3 antibody at 20 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of Fibulin 3 in HeLa cells with Fibulin 3 antibody at 20 μg/mL.)

WB (Western Blot)

(Western blot analysis of Fibulin 3 in HeLa cell lysate with Fibulin 3 antibody at (A) 0.5 and (B) 1 μg/mL.)

Related Product Information for anti-EFEMP1 antibody

Fibulin 3 Antibody: Fibulin 3, also known as epidermal growth factor (EGF)-containing fibulin-like extracellular matrix protein 1 (EFEMP1), is a member of the fibulin family of extracellular glycoproteins, a group of proteins that are widely distributed and frequently associated with vascular and elastic tissues. The fibulin proteins typically contain a tandem array of EGF-like repeats and a fibulin-type COOH-terminal module. Aberrant accumulation of Fibulin 3 in the endoplasmic reticulum of retinal pigment epithelial cells has been shown to be associated with inherited forms of macular degeneration, but the loss of Fibulin 3 expression does not lead to macular degeneration but rather the appearance of hernias due to a reduction of elastic fibers of fascial connective tissue. Recent experiments have shown that expression of Fibulin 3 promotes tumor growth and may thus be a therapeutic target.

NCBI and Uniprot Product Information

• NCBI GI #: 9665262
• NCBI GeneID: 2202
• NCBI Accession #: NP_001034437
• NCBI GenBank Nucleotide #: NM_004105.3
• UniProt Accession #: Q12805; Q541U7; A8K3I4; B4DW75; D6W5D2
• Molecular Weight: Predicted: 52 kDa; ; Observed: 47 kDa
• NCBI Official Synonym Full Names: EGF containing fibulin-like extracellular matrix protein 1
• NCBI Official Symbol: EFEMP1
• NCBI Official Synonym Symbols: DHRD; DRAD; FBNL; MLVT; MTLV; S1-5; FBLN3; FIBL-3
• NCBI Protein Information: EGF-containing fibulin-like extracellular matrix protein 1
• UniProt Protein Name: EGF-containing fibulin-like extracellular matrix protein 1
• UniProt Gene Name: EFEMP1
• UniProt Synonym Gene Names: FBLN3; FBNL; FIBL-3
• UniProt Entry Name: FBLN3_HUMAN