WB (Western Blot)
(Detection of human FKBP5/FKBP51 by western blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and HEK293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-FKBP5/FKBP51 antibody AAA211470 (lot AAA211470-1) used for WB at 0.04 ug/ml. Detection: Chemiluminescence with exposure time of 3 seconds.)
Rabbit anti-Human FKBP5/FKBP51 Polyclonal Antibody | anti-FKBP5/FKBP51 antibody
Rabbit anti-FKBP5/FKBP51 Antibody, Affinity Purified
Reactivity
Human
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
FKBP5/FKBP51, Antibody; Rabbit anti-FKBP5/FKBP51 Antibody, Affinity Purified; HSP90-binding immunophilin; peptidylprolyl cis-trans isomerase; PPIase; PPIase FKBP5; Ptg-10; T-cell FK506-binding protein; FKBP54; P54; rotamase; 54 kDa progesterone receptor-associated immunophilin; 51 kDa FK506-binding protein; peptidyl-prolyl cis-trans isomerase FKBP5; FKBP-51; 51 kDa FKBP; AIG6; androgen-regulated protein 6; FF1 antigen; FK506-binding protein 5; FKBP-5; FKBP51; Peptidyl-prolyl cis-trans isomerase FKBP5; FK506 binding protein 5; anti-FKBP5/FKBP51 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Concentration
200ug/ml (varies by lot)
Applicable Applications for anti-FKBP5/FKBP51 antibody
IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot)
Predicted Reactivity
Orangutan
Immunogen
Between 407 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human FKBP5/FKBP51 by western blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and HEK293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-FKBP5/FKBP51 antibody AAA211470 (lot AAA211470-1) used for WB at 0.04 ug/ml. Detection: Chemiluminescence with exposure time of 3 seconds.)
WB (Western Blot)
(Detection of human FKBP5/FKBP51 by western blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and HEK293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-FKBP5/FKBP51 antibody AAA211470 (lot AAA211470-1) used for WB at 0.04 ug/ml. Detection: Chemiluminescence with exposure time of 3 seconds.)
IP (Immunoprecipitation)
(Detection of human FKBP5/FKBP51 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-FKBP5/FKBP51 antibody AAA211470 (lot AAA211470-1) used for IP at 3 ug/mg lysate. FKBP5/FKBP51 was also immunoprecipitated by rabbit anti-FKBP5/FKBP51 antibody which recognizes an upstream epitope. For blotting immunoprecipitated FKBP5/FKBP51, AAA211470 was used at 1.0 ug/ml. Detection: Chemiluminescence with exposure time of 3 seconds.)
IP (Immunoprecipitation)
(Detection of human FKBP5/FKBP51 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-FKBP5/FKBP51 antibody AAA211470 (lot AAA211470-1) used for IP at 3 ug/mg lysate. FKBP5/FKBP51 was also immunoprecipitated by rabbit anti-FKBP5/FKBP51 antibody which recognizes an upstream epitope. For blotting immunoprecipitated FKBP5/FKBP51, AAA211470 was used at 1.0 ug/ml. Detection: Chemiluminescence with exposure time of 3 seconds.)
IHC (Immunohistochemistry)
(Detection of human FKBP5/FKBP51 by immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-FKBP5/FKBP51 (Cat. No. AAA211470 lot 1) used at a dilution of 1:1,000 (0.2ug/ml). Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human FKBP5/FKBP51 by immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-FKBP5/FKBP51 (Cat. No. AAA211470 lot 1) used at a dilution of 1:1,000 (0.2ug/ml). Detection: DAB)
Related Product Information for anti-FKBP5/FKBP51 antibody
FKBP5/FKBP51 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP5/FKBP51 exhibits peptidyl-prolyl cis-trans isomerase activity. The most studied role of FKBP5/FKBP51 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperones Hsp90 and Hsp70, FKBP5/FKBP51 is able to influence steroid-hormone binding affinity and transcriptional activity. Recently, FKBP5/FKBP51 has become of interest in the field of psychiatry due to its potential role in cortisol regulation and its relation to mood disorders.
Product Categories/Family for anti-FKBP5/FKBP51 antibody
NCBI and Uniprot Product Information
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Product Notes
The FKBP5/FKBP51 fkbp5 (Catalog #AAA211470) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-FKBP5/FKBP51 Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FKBP5/FKBP51 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the FKBP5/FKBP51 fkbp5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FKBP5/FKBP51, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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