IHC (Immunohistochemisry)
(Immunofluorescent analysis of PC3 cells using AAA232488 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Rabbit anti-Human FOXP1 Polyclonal Antibody | anti-FOXP1 antibody
FOXP1 Antibody
Gene Names
FOXP1; MFH; QRF1; 12CC4; hFKH1B; HSPC215
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
FOXP1, Antibody; FOXP1 Antibody; Forkhead box protein P1; Mac-1-regulated forkhead; FOXP1; HSPC215; anti-FOXP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
114
Applicable Applications for anti-FOXP1 antibody
ELISA
Immunogen
Recombinant Human Forkhead box protein P1 protein (541-677AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-31731 / sc-31736 / sc-376650 / sc-66896
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohistochemisry)
(Immunofluorescent analysis of PC3 cells using AAA232488 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
IHC (Immunohistochemisry)
(Immunofluorescent analysis of PC3 cells using AAA232488 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of human testis tissue using AAA232488 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of human testis tissue using AAA232488 at dilution of 1:100)
WB (Western Blot)
(Western BlotPositive WB detected in: Rat lung tissue,Mouse lung tissueAll lanes: FOXP1 antibody at 2ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 76,55,66,75,13,67,78 KDaObserved band size: 76 KDa)
WB (Western Blot)
(Western BlotPositive WB detected in: Rat lung tissue,Mouse lung tissueAll lanes: FOXP1 antibody at 2ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 76,55,66,75,13,67,78 KDaObserved band size: 76 KDa)
Related Product Information for anti-FOXP1 antibody
Transcriptional repressor (PubMed: 18347093, PubMed: 26647308). Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential (By similarity). Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. Involved in regulation of cardiac muscle cell proliferation. Involved in the columnar organization of spinal motor neurons. Promotes the formation of the lateral motor neuron column (LMC) and the preganglionic motor column (PGC) and is required for respective appropriate motor axon projections. The segment-appropriate generation of spinal chord motor columns requires cooperation with other Hox proteins. Can regulate PITX3 promoter activity; may promote midbrain identity in embryonic stem cell-derived dopamine neurons by regulating PITX3. Negatively regulates the differentiation of T follicular helper cells T(FH)s. Involved in maintainance of hair follicle stem cell quiescence; the function probably involves regulation of FGF18 (By similarity). Represses transcription of various pro-apoptotic genes and cooperates with NF-kappa B-signaling in promoting B-cell expansion by inhibition of caspase-dependent apoptosis (PubMed: 25267198). Binds to CSF1R promoter elements and is involved in regulation of monocyte differentiation and macrophage functions; repression of CSF1R in monocytes seems to involve NCOR2 as corepressor (PubMed: 15286807, PubMed: 18799727, PubMed: 18347093). Involved in endothelial cell proliferation, tube formation and migration indicative for a role in angiogenesis; the role in neovascularization seems to implicate suppression of SEMA5B (PubMed: 24023716). Can negatively regulate androgen receptor signaling (PubMed: 18640093).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
77,249 Da
NCBI Official Full Name
forkhead box protein P1 isoform 2
NCBI Official Synonym Full Names
forkhead box P1
NCBI Official Symbol
FOXP1
NCBI Official Synonym Symbols
MFH; QRF1; 12CC4; hFKH1B; HSPC215
NCBI Protein Information
forkhead box protein P1
UniProt Protein Name
Forkhead box protein P1
UniProt Gene Name
FOXP1
UniProt Synonym Gene Names
MFH
UniProt Entry Name
FOXP1_HUMAN
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Product Notes
The FOXP1 foxp1 (Catalog #AAA232488) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FOXP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FOXP1 can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the FOXP1 foxp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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